1548-74-9 Usage
Description
4-AMINO-2,3,5,6-TETRAFLUOROBENZAMIDE is a beige crystalline powder that serves as a valuable intermediate in the synthesis of aromatic polyfluoronitroso compounds. Its unique chemical structure, featuring a benzene ring with four fluorine atoms and an amide functional group, makes it a versatile building block for various chemical reactions and applications.
Uses
Used in Chemical Synthesis:
4-AMINO-2,3,5,6-TETRAFLUOROBENZAMIDE is used as a key intermediate in the chemical synthesis of aromatic polyfluoronitroso compounds. Its fluorinated nature and amide functionality contribute to the development of novel molecules with potential applications in various fields, such as pharmaceuticals, agrochemicals, and materials science.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-AMINO-2,3,5,6-TETRAFLUOROBENZAMIDE is used as a starting material for the development of new drugs with improved properties, such as enhanced bioavailability, selectivity, and potency. The fluorination of the benzene ring can lead to increased metabolic stability and better penetration across biological membranes, which are crucial factors for drug efficacy.
Used in Agrochemical Industry:
4-AMINO-2,3,5,6-TETRAFLUOROBENZAMIDE is also utilized in the agrochemical industry for the synthesis of novel pesticides and herbicides. The introduction of fluorine atoms can enhance the lipophilicity and volatility of the resulting compounds, leading to improved performance and selectivity in controlling pests and weeds.
Used in Materials Science:
In the field of materials science, 4-AMINO-2,3,5,6-TETRAFLUOROBENZAMIDE can be employed in the development of advanced materials with unique properties, such as high thermal stability, chemical resistance, and low dielectric constants. These materials can find applications in various industries, including electronics, aerospace, and automotive.
Check Digit Verification of cas no
The CAS Registry Mumber 1548-74-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,4 and 8 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1548-74:
(6*1)+(5*5)+(4*4)+(3*8)+(2*7)+(1*4)=89
89 % 10 = 9
So 1548-74-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H4F4N2O/c8-2-1(7(13)14)3(9)5(11)6(12)4(2)10/h12H2,(H2,13,14)
1548-74-9Relevant articles and documents
Selective ruthenium-catalyzed hydration of nitriles to amides in pure aqueous medium under neutral conditions
Cadierno, Victorio,Francos, Javier,Gimeno, Jose
scheme or table, p. 6601 - 6605 (2009/07/10)
A study was conducted to demonstrate that water-soluble ruthenium(II) complexes can be used as catalysts for the hydration of nitriles in pure aqueous media and under neutral conditions. The hydration of benzonitrile was investigated as a model reaction and the ruthenium precursor was added to a 0.33M aqueous solution of benzonitrile at 100°C, while the reaction was monitored by gas chromatography. All the complexes checked, were found to be active and selective catalysts in the hydration process, providing benzamide as a specific reaction product. The most relevant results were obtained by using ruthenium complexes, bearing a nitrogen-containing ligand, which led to appropriate production of benzamide. The most effective ruthenium complex was found to be an efficient catalyst for the selective hydration of a large number of other nitriles.
