15506-18-0

Basic information

• Product Name: 3-pyridinecarboxylic acid, 1,2-dihydro-1-methyl-2-oxo-
• Synonyms: 1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid;3-pyridinecarboxylic acid, 1,2-dihydro-1-methyl-2-oxo-;1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid(SALTDATA: FREE);1-methyl-2-oxo-3-pyridinecarboxylic acid;1-methyl-2-oxo-pyridine-3-carboxylic acid;1-methyl-2-oxopyridine-3-carboxylic acid;2-keto-1-methyl-nicotinic acid;AJ-333/25006182
• CAS NO: 15506-18-0
• Molecular Formula: C₇H₇NO₃
• Molecular Weight: 153.13538
• Mol File: 15506-18-0.mol
• Article Data: 15

Chemical Properties

• Melting Point: 184 °C
• Boiling Point: 369.3±35.0 °C(Predicted)
• Appearance: /
• Density: 1.381±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.45±0.20(Predicted)
• CAS DataBase Reference: 3-pyridinecarboxylic acid, 1,2-dihydro-1-methyl-2-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-pyridinecarboxylic acid, 1,2-dihydro-1-methyl-2-oxo-(15506-18-0)
• EPA Substance Registry System: 3-pyridinecarboxylic acid, 1,2-dihydro-1-methyl-2-oxo-(15506-18-0)

Safety Data

• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 15506-18-0(Hazardous Substances Data)

Usage

General Description

3-Pyridinecarboxylic acid, 1,2-dihydro-1-methyl-2-oxo-, also known as niacinamide or nicotinamide, is an essential vitamin B3 compound that plays a crucial role in various biochemical processes in the body. It is a water-soluble vitamin that is important for maintaining the health of the skin, nervous system, and digestive system. Niacinamide is commonly used in skincare products for its ability to improve the appearance of aging skin, reduce hyperpigmentation, and strengthen the skin's barrier function. It is also used as a nutritional supplement to prevent and treat vitamin B3 deficiency and related conditions such as pellagra. Additionally, niacinamide has been studied for its potential anti-inflammatory and antioxidant properties, making it a popular ingredient in a wide range of skincare and pharmaceutical products.

Upstream product

• 10128-91-3 methyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile 
• 609-71-2 1,2-dihydro-2-oxonicotinic acid 
• 74-88-4 methyl iodide 
• 67367-27-5 methyl 1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate 
• 98-92-0 nicotinamide 
• 6456-44-6 N-methylnicotineamide iodide 
• 609-71-2 2-hydroxy-3-carboxypyridine 
• 74-83-9 methyl bromide 
• 124-41-4 sodium methylate 
• 61856-47-1 3-formyl-1-methyl-2(1H)-pyridinethione 
• 769-09-5 1-methyl-2-oxopyridine-3-carboxamide 
• 13362-27-1 2-imino-1-methyl-1,2-dihydro-pyridine-3-carboxylic acid 

Relevant articles and documents

-

-

IMMUNOMODULATORY COMPOUNDS

Disclosed are immunomodulatory compounds, pharmaceutical compositions containing them, and methods of making and using the compounds to treat diseases and disorders characterized by aberrant protein activity that can be targeted by cereblon.

MORPHINAN DERIVATIVE

A morphinan derivative represented by the following general formula (I): (wherein R1 represents hydrogen, C1-10 alkyl, cycloalkylalkyl where the cycloalkyl moiety has 3 to 6 carbon atoms, and the alkylene moiety has 1 to 5 carbon atoms, etc., R2 represents heterocyclic ring containing 1 to 4 heteroatoms selected from N, O and S and at least one carbon atom as ring-constituting atoms, containing at least one set of adjacent ring-constituting atoms bound by a double bond, and further substituted with at least one oxo group, Y binds to a carbon atom as a ring-constituting atom of R2, R3, R4, and R5 represent hydrogen; hydroxy, etc., R6a and R6b represent hydrogen, etc., R7 and R8 represent hydrogen, etc., R9 and R10, which are the same or different, represent hydrogen, etc., X represents O or CH2, and Y represents C(=O)), a tautomer or stereoisomer of the compound, or a pharmaceutically acceptable salt thereof, or a solvate thereof is used as an anxiolytic drug, antidepressant, etc.