1553930-25-8Relevant articles and documents
Enhancing a CH-π interaction to increase the affinity for 5-HT 1A receptors
Liegeois, Jean-Francois,Lespagnard, Marc,Meneses Salas, Elsa,Mangin, Floriane,Scuvee-Moreau, Jacqueline,Dilly, Sebastien
, p. 358 - 362 (2014/05/06)
An electrostatic interaction related to a favorable position of the distal phenyl ring and a phenylalanine residue in the binding pocket would explain the higher 5-HT1A affinity of a 4-phenyl-1,2,3,6-tetrahydropyridine (THP) analogue compared t