155394-02-8

Basic information

• Product Name: 3-Octanol, 2-[(R)-(4-methylphenyl)sulfinyl]-1-(trimethylsilyl)-, (2R,3R)-
• CAS NO: 155394-02-8
• Molecular Formula: C18H32O2SSi
• Molecular Weight: 340.602
• Mol File: 155394-02-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Octanol, 2-[(R)-(4-methylphenyl)sulfinyl]-1-(trimethylsilyl)-, (2R,3R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Octanol, 2-[(R)-(4-methylphenyl)sulfinyl]-1-(trimethylsilyl)-, (2R,3R)-(155394-02-8)
• EPA Substance Registry System: 3-Octanol, 2-[(R)-(4-methylphenyl)sulfinyl]-1-(trimethylsilyl)-, (2R,3R)-(155394-02-8)

Safety Data

• Hazardous Substances Data: 155394-02-8(Hazardous Substances Data)

Upstream product

• 1519-39-7 (R)-methyl p-tolyl sulfoxide 
• 123-66-0 Ethyl hexanoate 
• 153123-09-2 (R_S)-p-Tolyl β-(trimethylsilyl)ethyl sulfoxide 
• 66-25-1 hexanal 

Downstream Products

• 3391-86-4 (R)-1-octene-3-ol 

Relevant articles and documents

Asymmetric reduction of α-(trimethylsilyl)methyl-β-ketosulfoxide with DIBAL under basic conditions

The reaction of the α-carbanion of p-tolyl 2-(trimethylsilyl)ethyl sulfoxide with esters followed by reduction with DIBAL gave α-(trimethylsilyl)methyl-β-hydroxysulfoxides with high stereoselectivity. The stereoselective reaction was demonstrated to proceed through a dynamic kinetic resolution pathway via a six-membered cyclic transition state involving Si-O interaction. These reactions provide a convenient route for the synthesis of optically pure allylic alcohols.