1554458-53-5 Usage
Description
BAY-1217389, also known as N-Cyclopropyl-4-[6-(2,3-difluoro-4-methoxyphenoxy)-8-[(3,3,3-trifluoropropyl)amino]imidazo[1,2-b]pyridazin-3-yl]-2-methylbenzamide, is a chemical compound with potent antitumor properties. It functions by inhibiting monopolar spindle 1, a serine/threonine/tyrosine kinase that plays a crucial role in cell division. This inhibition can lead to the disruption of cancer cell proliferation, making BAY-1217389 a promising candidate for cancer treatment.
Uses
Used in Pharmaceutical Industry:
BAY-1217389 is used as an antitumor agent for its ability to inhibit monopolar spindle 1, a key enzyme involved in cell division. By targeting this enzyme, BAY-1217389 demonstrates potential in treating various types of cancer by disrupting the uncontrolled cell division characteristic of malignant cells.
Used in Cancer Research:
In the field of cancer research, BAY-1217389 serves as a valuable tool for studying the role of monopolar spindle 1 in cancer cell division and the potential of targeting this enzyme for therapeutic intervention. BAY-1217389 can help researchers better understand the molecular mechanisms underlying cancer progression and identify new strategies for cancer treatment.
Used in Drug Development:
BAY-1217389 is utilized in the development of novel cancer therapeutics, as its mechanism of action offers a unique approach to targeting cancer cells. By inhibiting monopolar spindle 1, this compound has the potential to be developed into a new class of antitumor drugs, providing an alternative treatment option for patients with various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 1554458-53-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,5,4,4,5 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1554458-53:
(9*1)+(8*5)+(7*5)+(6*4)+(5*4)+(4*5)+(3*8)+(2*5)+(1*3)=185
185 % 10 = 5
So 1554458-53-5 is a valid CAS Registry Number.
1554458-53-5Relevant articles and documents
SUBSTITUTED IMIDAZOPYRIDAZINES
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, (2014/09/16)
The present invention relates to substituted imidazopyridazine compounds, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
COMBINATION OF A IMIDAZOPYRIDAZINE DERIVATIVE AND A MITOTIC AGENT FOR THE TREATMENT OF CANCER
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, (2015/01/09)
The present invention relates to a combination comprising an Mps-1 kinase inhibitor and a mitotic inhibitor. The present invention also relates to the use of said combination for the treatment of cancer, in particular of pancreatic cancer, glioblastoma, ovarian cancer, non-small cell lung carcinoma, breast cancer and/or gastric cancer.