1557-50-2

Basic information

• Product Name: Acetamide, N-[2-(phenylmethyl)phenyl]-
• CAS NO: 1557-50-2
• Molecular Formula: C15H15NO
• Molecular Weight: 225.29
• Mol File: 1557-50-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[2-(phenylmethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[2-(phenylmethyl)phenyl]-(1557-50-2)
• EPA Substance Registry System: Acetamide, N-[2-(phenylmethyl)phenyl]-(1557-50-2)

Safety Data

• Hazardous Substances Data: 1557-50-2(Hazardous Substances Data)

Upstream product

• 20939-77-9 2-acetamidobenzyl alcohol 
• 98-80-6 phenylboronic acid 
• 103-84-4 Acetanilid 
• 100-51-6 benzyl alcohol 
• 5840-40-4 2-nitrodiphenylmethane 
• 85730-27-4 N-Methylphenyl-N-chloro(phenylhydrazono)acetic acid ethyl ester 
• 61624-05-3 N-methylphenyl-N-phenylethoxalylhydrazine 
• 28059-64-5 2-benzylaniline 
• 108-24-7 acetic anhydride 

Downstream Products

• 1364188-14-6 N-(3-benzyl-2',4',6'-trimethylbiphenyl-4-yl)-N-mesitylacetamide 
• 1334607-43-0 N-(4-tert-butylphenyl)-N-(4-iodo-2,6-dimethylphenyl)acetamide 
• 1204312-37-7 N-acetyl-3-benzylanthranilic acid 
• 859791-38-1 2-amino-5-nitrodiphenylmethane 
• 13097-01-3 3-phenyl-1H-indazole 
• 142835-46-9 2-amino-4',5-dinitrodiphenylmethane 
• 142835-44-7 2-amino-4'-nitrodiphenylmethane 
• 142835-43-6 2-acetamido-4'-nitrodiphenylmethane 
• 142835-42-5 2-acetamido-5-nitrodiphenylmethane 

Relevant articles and documents

Access to Chiral Seven-Member Cyclic Amines via Rh-Catalyzed Asymmetric Hydrogenation

A highly efficient asymmetric hydrogenation of azepine/oxazepine-type seven-member cyclic imine hydrochlorides was successfully developed using Rh/bisphosphine-thiourea ligand ZhaoPhos, affording various chiral seven-member cyclic amines with full conversions, high yields, and excellent enantioselectivities (up to 96% yield, >99% ee). Additionally, this asymmetric hydrogenation can proceed well on gram scale with excellent ee value. Moreover, control experimental results displayed that the anion-bonding interaction between the chloride ion of the substrate and thiourea motif of the ZhaoPhos played an important role to obtain excellent enantioselectivity.

Solvent free acid catalysed direct N-alkylation of amines with alcohols using Al grafted MCM-41

The catalytic activity of Al grafted MCM-41 (Al-MS) was explored for solvent free acid catalysed direct N-alkylation of amines using alcohols as green alkylating agent to establish a clean method for synthesis of N-alkylated amines. The study revealed that acidity of Al-MS catalyst, reaction conditions and substrate's (amines and alcohols) nature are important factors influencing the N-alkylation reaction. The Al grafted MCM-41 with Si/Al molar ratio of 5 showed excellent activity for N-alkylation of amines with alcohols. The reusability of spent catalyst regenerated by simple washing with acetone was demonstrated for subsequent four reaction cycles.