1559077-94-9

Basic information

• Product Name: (E)-1-bromo-3-(3,3,3-trifluoroprop-1-en-1-yl)benzene
• Synonyms: (E)-1-bromo-3-(3,3,3-trifluoroprop-1-en-1-yl)benzene
• CAS NO: 1559077-94-9
• Molecular Weight: 251.046
• Mol File: 1559077-94-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (E)-1-bromo-3-(3,3,3-trifluoroprop-1-en-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-bromo-3-(3,3,3-trifluoroprop-1-en-1-yl)benzene(1559077-94-9)
• EPA Substance Registry System: (E)-1-bromo-3-(3,3,3-trifluoroprop-1-en-1-yl)benzene(1559077-94-9)

Safety Data

• Hazardous Substances Data: 1559077-94-9(Hazardous Substances Data)

Upstream product

• 14473-91-7 3-bromocinnamic acid 
• 2926-29-6 Langlois reagent 
• 3132-99-8 m-bromobenzoic aldehyde 
• 371-67-5 2,2,2-trifluorodiazoethane 
• 2314-97-8 iodotrifluoromethane 
• 2039-86-3 3-bromostyrene 
• 887144-97-0 Togni's reagent 
• 887144-94-7 Togni's reagent II 

Relevant articles and documents

Electrochemical Synthesis Strategy for Cvinyl-CF3 Compounds through Decarboxylative Trifluoromethylation

An efficient decarboxylative trifluoromethylation of α,β-unsaturated carboxylic acids using the Langlois reagent as a trifluoromethyl precursor has been achieved by an electro-oxidative strategy. Under catalyst-free and external oxidant-free electrolysis

Practical Photocatalytic Trifluoromethylation and Hydrotrifluoromethylation of Styrenes in Batch and Flow

Styrenes represent a challenging class of substrates for current radical trifluoromethylation and hydrotrifluoromethylation methods due to a myriad of potential side reactions. Herein, we describe the development of mild, selective and broadly applicable photocatalytic trifluoromethylation and hydrotrifluoromethylation protocols for these challenging substrates. The methods use fac-Ir(ppy)3, visible light and inexpensive CF3I and can be applied to a diverse set of vinylarene substrates. The use of continuous-flow photochemical reaction conditions allowed to reduce the reaction time and increase the reaction selectivity.

Copper-catalyzed trifluoromethylation of alkenes with an electrophilic trifluoromethylating reagent

An efficient method for the copper-catalyzed trifluoromethylation of terminal alkenes with an electrophilic trifluoromethylating reagent has been developed. The reactions proceeded smoothly to give trifluoromethylated alkenes in good to excellent yields. The results provided a versatile approach for the construction of Cvinyl-CF3 bonds without using prefunctionalized substrates.