156094-77-8

Basic information

• Product Name: 3-Pyridinecarboxaldehyde, 6-methoxy-2-methyl- (9CI)
• Synonyms: 3-Pyridinecarboxaldehyde, 6-methoxy-2-methyl- (9CI);6-Methoxy-2-methylpyridine-3-carboxaldehyde;6-methoxy-2-methyl nicotinaldehyde;3-Pyridinecarboxaldehyde, 6-Methoxy-2-Methyl-;6-METHOXY-2-METHYL-3-PYRIDINECARBOXALDEHYDE;6-Methoxy-2-methyl-pyridine-3-carbaldehyde
• CAS NO: 156094-77-8
• Molecular Formula: C₈H₉NO₂
• Molecular Weight: 151.16256
• Product Categories: ALDEHYDE
• Mol File: 156094-77-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 254.9°C at 760 mmHg
• Flash Point: 108°C
• Appearance: /
• Density: 1.123g/cm³
• Vapor Pressure: 0.0168mmHg at 25°C
• Refractive Index: 1.545
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-Pyridinecarboxaldehyde, 6-methoxy-2-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxaldehyde, 6-methoxy-2-methyl- (9CI)(156094-77-8)
• EPA Substance Registry System: 3-Pyridinecarboxaldehyde, 6-methoxy-2-methyl- (9CI)(156094-77-8)

Safety Data

• Hazardous Substances Data: 156094-77-8(Hazardous Substances Data)

Usage

General Description

3-Pyridinecarboxaldehyde, 6-methoxy-2-methyl- (9CI) is a chemical compound with the molecular formula C8H9NO2. It is a derivative of pyridinecarboxaldehyde with a methoxy and methyl group attached to the 6th and 2nd carbon atoms, respectively. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Its unique structure and properties make it useful in various chemical reactions and processes. Additionally, it is important to handle this compound with caution as it may have potential health and safety hazards.

InChI:InChI=1/C8H9NO2/c1-6-7(5-10)3-4-8(9-6)11-2/h3-5H,1-2H3

Upstream product

• 63071-03-4 2-methoxy-6-methyl-pyridine 
• 3279-76-3 6-hydroxy-2-methylpyridine 
• 126717-59-7 3-bromo-6-methoxy-2-methylpyridine 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1211588-74-7 3-ethynyl-6-methoxypicoline 
• 32383-10-1 3-Hydroxymethyl-6-methoxy-2-methylpyridin 
• 875757-96-3 1-(6-methoxy-2-(phenylselenylmethyl)pyridin-3-yl)cyclohex-3-en-1-ol 
• 875757-98-5 1-(6-methoxy-2-methylpyridin-3-yl)cyclohex-3-enol 

Relevant articles and documents

INHIBITOR OF CASEIN KINASE 1DELTA AND CASEIN KINASE 1EPSILON

There is provided an inhibitor that inhibits casein kinase 1δ and casein kinase 1ε, and thus, there is also provided a pharmaceutical agent useful for the treatment and/or prevention of a disease, with the pathological condition of which the mechanism of activation of casein kinase 1δ or casein kinase 1ε is associated. Particularly, the above-described inhibitor is used to provide a pharmaceutical agent useful for the treatment of circadian rhythm disorder (including sleep disorder), central neurodegenerative disease, and cancer. An inhibitor of casein kinase 1δ and casein kinase 1ε, which comprises, as an active ingredient, an oxazolone derivative represented by the following general formula (1), a salt thereof, a solvate thereof, or a hydrate thereof: [wherein, in the formula (1), each of R1 and R2 independently represents any one of a substituted or unsubstituted 6-membered or 5-membered heterocyclic group optionally having a condensed ring, a substituted or unsubstituted aromatic hydrocarbon group optionally having a condensed ring, and a substituted or unsubstituted aromatic hydrocarbon lower alkyl group or aromatic hydrocarbon lower alkenyl group optionally having a condensed ring.]

A radical mediated approach to the core structure of huperzine A

The synthesis of the core structure of huperzine A by cyclisation of 2-pyridylmethyl radicals is described. (2-Methylpyridin-3-yl)cyclohexenols are directly selenated at the benzylic position by deprotonation/selenation and the products undergo either 5-e

Functionalisation of 2-methoxy-6-methylpyridine

Selective bromination of 2-methoxy-6-methylpyridine 2 afforded 5-bromo-2- methoxy-6-methylpyridine 8. Deprotonation of this pyridine derivative in benzylic position or lithium-bromine exchange allowed the regio-selective introduction of various electrophiles.