15625-88-4

Basic information

• Product Name: 1H-1,2,4-Triazole,1-acetyl-(6CI,7CI,8CI,9CI)
• Synonyms: 1H-1,2,4-Triazole,1-acetyl-(6CI,7CI,8CI,9CI);1-Acetyl-1H-1,2,4-triazole;1-(1H-1,2,4-Triazol-1-yl)ethan-1-one;1-(1H-1,2,4-triazol-1-yl)ethanone
• CAS NO: 15625-88-4
• Molecular Formula: C₄H₅N₃O
• Molecular Weight: 111.1
• Product Categories: TRIAZOLE
• Mol File: 15625-88-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 41-42 °C
• Boiling Point: 241.6°Cat760mmHg
• Flash Point: 99.9°C
• Appearance: /
• Density: 1.31g/cm³
• Vapor Pressure: 0.0356mmHg at 25°C
• Refractive Index: 1.604
• PKA: 0.90±0.10(Predicted)
• CAS DataBase Reference: 1H-1,2,4-Triazole,1-acetyl-(6CI,7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,2,4-Triazole,1-acetyl-(6CI,7CI,8CI,9CI)(15625-88-4)
• EPA Substance Registry System: 1H-1,2,4-Triazole,1-acetyl-(6CI,7CI,8CI,9CI)(15625-88-4)

Safety Data

• Hazardous Substances Data: 15625-88-4(Hazardous Substances Data)

Usage

General Description

1H-1,2,4-Triazole,1-acetyl, also known as 1-acetyl-1H-1,2,4-triazole, is a chemical compound with the molecular formula C4H5N3O. It is a derivative of triazole and is commonly used in pharmaceuticals and agrochemicals. 1H-1,2,4-Triazole,1-acetyl-(6CI,7CI,8CI,9CI) has antifungal, anticancer, and antiviral properties, and is used in the synthesis of various pharmaceutical products. It is also used as a building block in organic chemistry for the synthesis of other complex compounds. Additionally, 1H-1,2,4-Triazole,1-acetyl is considered to be a potential mutagen and carcinogen, leading to it being regulated in some countries due to its toxic and hazardous nature.

InChI:InChI=1/C4H5N3O/c1-4(8)7-3-5-2-6-7/h2-3H,1H3

Upstream product

• 288-88-0 1,2,4-Triazole 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 18293-54-4 1-trimethylsilyl-1,2,4-triazole 
• 64-19-7 acetic acid 
• 175351-39-0 1-cyano-1,2,4-triazole 

Downstream Products

• 2050-43-3 N-(2,4-dimethylphenyl)acetamide 
• 103-84-4 Acetanilid 
• 66333-88-8 5-methylisoxazole 
• 288-88-0 1,2,4-Triazole 
• 64-19-7 acetic acid 
• 463-51-4 Ketene 

Relevant articles and documents

N-Cyanazoles in Synthesis of Amides of Carboxylic Acids

The reaction of carboxylic acids with 1-cyanimidazole, 1-cyanobenzimidazole, and 1-cyano-1,2,4-triazole leads to the formation of 1-acylazoles used in situ in synthesis of anilides of the corresponding carboxylic acids.

ETUDE DANS LA SERIE DES ORGANOSILYLAZOLES I. ACTION DES HALOGENURES D'ALKYLE, DES CHLORURES D'ACIDE ET DES CETONES HALOGENEES

The reactivity of organosilylamines of imidazole, pyrazole, 1,2,4-triazole and benzotriazole towards alkyl halides, acidic chlorides and halogenated ketones has been studied.Except for 1-trimethylsilylimidazole, which gives a mixed quaternary salt, reactions with primary halides lead to the corresponding 1-alkylated heterocyclic compounds in high yields; in each case only one isomer is obtained (1-alkyl-1,2,4-triazole and 1-alkylbenzotriazole).Similarly acidic chlorides give 1-acylated derivatives in quantitative yields.Finally α- or β-halogenated ketones show different behaviour and give the addition or substitution products.