156311-83-0 Usage
Description
(3-Hydroxy-3H-1,2,3-triazolo[4,5-b]pyridinato-O)tri-1-pyrrolidinylphosphonium hexafluorophosphate, also known as PyAOP, is a phosphonium salt that is used as a coupling reagent in solid-phase peptide synthesis. It is a white to off-white crystalline powder and is preferred over HATU due to its lack of side reactions at the N-terminus of the peptide. PyAOP is a derivative of HOAt (H805070) and is more reactive compared to the HOBt derivates because of the additional nitrogen.
Uses
Used in Pharmaceutical Industry:
PyAOP is used as a coupling reagent in solid-phase peptide synthesis for the production of various pharmaceutical compounds. It is favored for its ability to avoid side reactions with the amino terminus of the peptide, which can be a common issue with other coupling reagents like HATU.
Used in Research and Development:
In the field of research and development, PyAOP is utilized for the synthesis of peptides and other bioactive molecules. Its high reactivity and selectivity make it a valuable tool for creating complex molecular structures with minimal side reactions.
Used in Chemical Synthesis:
PyAOP is also used in chemical synthesis processes, particularly in the creation of complex organic molecules. Its reactivity and selectivity make it a preferred choice for chemists working on the development of new compounds and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 156311-83-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,3,1 and 1 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 156311-83:
(8*1)+(7*5)+(6*6)+(5*3)+(4*1)+(3*1)+(2*8)+(1*3)=120
120 % 10 = 0
So 156311-83-0 is a valid CAS Registry Number.
InChI:InChI=1/C17H27N7OP.F6P/c1-2-11-21(10-1)26(22-12-3-4-13-22,23-14-5-6-15-23)25-24-17-16(19-20-24)8-7-9-18-17;1-7(2,3,4,5)6/h7-9H,1-6,10-15H2;/q+1;-1
