156547-56-7

Basic information

• Product Name: FSCPX
• Synonyms: 8-cyclopentyl-3-(3-((4-(fluorosulfonyl)benzoyl)oxy)propyl)-1-propylxanthine
• CAS NO: 156547-56-7
• Molecular Formula: C23F1H27N4O6S1
• Molecular Weight: 506.55
• Mol File: 156547-56-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 730.7°Cat760mmHg
• Flash Point: 395.7°C
• Appearance: yellow/solid
• Density: 1.378g/cm³
• Vapor Pressure: 3.28E-21mmHg at 25°C
• Refractive Index: 1.582
• Solubility: DMSO: 10 mg/mL, soluble
• PKA: 8.69±0.70(Predicted)
• CAS DataBase Reference: FSCPX(CAS DataBase Reference)
• NIST Chemistry Reference: FSCPX(156547-56-7)
• EPA Substance Registry System: FSCPX(156547-56-7)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 156547-56-7(Hazardous Substances Data)

Usage

Uses

FSCPX is an irreversible A1 adenosine receptor antagonist.

InChI:InChI=1/C23H27FN4O6S/c1-2-12-28-21(29)18-20(26-19(25-18)15-6-3-4-7-15)27(23(28)31)13-5-14-34-22(30)16-8-10-17(11-9-16)35(24,32)33/h8-11,15H,2-7,12-14H2,1H3,(H,25,26)

Upstream product

• 344796-54-9 8-cyclopentyl-7-(4-methoxy-benzyl)-3-(3-methoxy-propyl)-1-propyl-3,7-dihydro-purine-2,6-dione 
• 344796-53-8 8-cyclopentyl-7-(4-methoxy-benzyl)-3-(3-methoxy-propyl)-3,7-dihydro-purine-2,6-dione 
• 158892-72-9 3-(3-methoxypropyl)-8-cyclopentylxanthine 
• 54052-61-8 5,6-diamino-1-(3-methoxy-propyl)-1H-pyrimidine-2,4-dione 
• 54052-66-3 6-amino-1-(3-methoxy-propyl)-5-nitroso-1H-pyrimidine-2,4-dione 
• 158893-39-1 6-amino-1-(3-methoxypropyl)uracil 
• 156547-49-8 PSB-16 
• 402-55-1 4-fluorosulfonylbenzoyl chloride 

Relevant articles and documents

Synthesis and use of FSCPX, an irreversible adenosine A1 antagonist, as a 'receptor knock-down' tool

A new preparative synthetic route for the irreversible adenosine A1 antagonist 8-cyclopentyl-3-N-[3-((3-(4-fluorosulphonyl)benzoyl)-oxy)-propyl]-1-N- propyl-xanthine (FSCPX, 1) is described. The availability of ample amounts of the irreversible antagonist FSCPX allowed us to use FSCPX as a research tool for adenosine A1 receptors in in vivo experiments. After verification of the irreversible antagonistic function of FSCPX in in vitro experiments, FSCPX was used successfully as a 'receptor knock-down' tool in in vivo experiments on conscious rats.