156558-16-6Relevant articles and documents
Stereoselective synthesis and thromboxane A2 (TXA2) receptor antagonistic activity of optically active phenol derivatives
Fukumoto, Shoji,Terashita, Zen-Ichi,Ashida, Yasuko,Terao, Shinji,Shiraishi, Mitsuru
, p. 749 - 755 (2007/10/03)
Enantiomers of four potent nonprostanoid thromboxane A2 (TXA2) receptor antagonists, (±)-7-(4-fluorophenyl)-7-(2-hydroxyphenyl)heptanoic acids (1- 4), were synthesized stereoselectively by direct ortho-alkylation of phenols under mod