15657-87-1

Basic information

• Product Name: 8-Quinolinol, 5-phenyl-
• CAS NO: 15657-87-1
• Molecular Formula: C15H11NO
• Molecular Weight: 221.258
• Mol File: 15657-87-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 8-Quinolinol, 5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Quinolinol, 5-phenyl-(15657-87-1)
• EPA Substance Registry System: 8-Quinolinol, 5-phenyl-(15657-87-1)

Safety Data

• Hazardous Substances Data: 15657-87-1(Hazardous Substances Data)

Upstream product

• 1134-36-7 2-amino-4-phenylphenol 
• 938-33-0 8-methoxyquinoline 
• 1198-14-7 5-bromo-8-hydroxyquinoline 
• 100-58-3 phenylmagnesium bromide 
• 1108187-78-5 5-phenylquinolin-8-yl 4-methylbenzenesulfonate 
• 202259-06-1 8-(benzyloxy)-5-bromoquinoline 
• 4688-74-8 phenylboric acid 
• 98-80-6 phenylboronic acid 
• 10522-47-1 5-bromo-8-methoxyquinoline 
• 13207-63-1 5-iodoquinolin-8-ol 
• 148-24-3 8-quinolinol 
• 892878-82-9 8-(tert-butyldimethylsilyloxy)-5-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)quinoline 
• 892878-80-7 8-(tert-butyldimethylsilyloxy)-5-iodoquinoline 
• 892878-84-1 8-(tert-butyldimethylsilyloxy)-5-phenylquinoline 

Downstream Products

• 116633-03-5 8-methoxy-5-phenylquinoline 
• 1403257-30-6 (5-phenyl-8-quinolinolato)(hydrido)(carbonyl)bis(triphenylphosphine)ruthenium(II) 
• 1245934-88-6 N,N'-bis((5-phenyl-8-hydroxy-7-quinolinyl)methyl)-1,10-diaza-18-crown-6 ether 
• 20959-66-4 tetrakis(5-phenyl-8-quinolinolato)thorium(IV) * 5-phenyl-8-quinolinol 
• 33907-97-0 UO₂(C₁₅H₁₀NO)2*C₁₅H₁₁NO 

Relevant articles and documents

Synthesis of 5-substituted quinolim-8-ols

A new preparative procedure for 5-aryl- or 5-decylquinolin-8-ols was developed. The key step of the procedure is the cross coupling of 8-benzyloxy-5-bromoquinoline with arylboronic acid or 9-decyl-9-borabicyclo[3.3.1]nonane (Suzuki reaction). Deprotection

Iron-Catalyzed Room Temperature Cross-Couplings of Bromophenols with Aryl Grignard Reagents

Herein we report a room temperature Fe-catalyzed coupling reaction of various bromophenols with aryl Grignard reagents, which exhibits a wide substrate scope and high functional group tolerance. For the first time, the combination of simple Fe(acac)3/PBu3/Ti(OEt)4 has been used as an effective catalyst for the biaryl couplings of bromophenols or their Na or K salts with debromination and etherification side reactions being well suppressed. Various biphenols including natural product garcibiphenyl C as well as pharmaceutical diflunisal and its ethyl ester were facilely synthesized using the present protocol. (Figure presented.).

Diboron and triboron compounds based on linear and star-shaped conjugated ligands with 8-hydroxyquinolate functionality: Impact of intermolecular interaction and boron coordination on luminescence

New 8-R-quinoline functionalized linear and star-shaped conjugated molecules have been synthesized using Suzuki-Miyaura coupling methods (R = MeO, L1-L5; R = CH3OCH2O, L1′-L5′). When treated with HCl, L1′-L5′ are converted readily to