156571-46-9 Usage
Description
7-DIETHYLAMINO-3-((((2-MALEIMIDYL)ETHYL)AMINO) CARBONYL)COUMARIN, also known as MDCC, is a thiol-reactive fluorescent probe derived from coumarin. It is characterized by its ability to selectively label thiol groups in proteins, making it a valuable tool in various research and diagnostic applications. Its unique chemical structure allows for specific interactions with target molecules, enhancing its utility in biological studies.
Uses
Used in Research Applications:
7-DIETHYLAMINO-3-((((2-MALEIMIDYL)ETHYL)AMINO) CARBONYL)COUMARIN is used as a thiol-reactive fluorescent probe for protein labeling. This application is particularly useful in studying protein structure, function, and interactions within biological systems. The probe's fluorescence properties enable real-time monitoring and analysis of protein dynamics.
Used in Diagnostic Applications:
MDCC is employed as a specific probe for inorganic phosphate detection. This use is crucial in various diagnostic assays and tests, as inorganic phosphate levels can be indicative of certain health conditions or metabolic imbalances. The probe's specificity and sensitivity contribute to accurate and reliable diagnostic outcomes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 7-DIETHYLAMINO-3-((((2-MALEIMIDYL)ETHYL)AMINO) CARBONYL)COUMARIN is used as a component in the development of novel drug delivery systems. Its ability to label proteins can be leveraged to improve the targeting and efficacy of therapeutic agents, potentially leading to more effective treatments for various diseases.
Used in Biotechnology Industry:
7-DIETHYLAMINO-3-((((2-MALEIMIDYL)ETHYL)AMINO) CARBONYL)COUMARIN is used as a tool in the biotechnology industry for the development of biosensors and diagnostic devices. Its thiol-reactive properties make it suitable for creating sensors that can detect specific biological molecules, which can be applied in various fields such as environmental monitoring, food safety, and medical diagnostics.
Check Digit Verification of cas no
The CAS Registry Mumber 156571-46-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,5,7 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 156571-46:
(8*1)+(7*5)+(6*6)+(5*5)+(4*7)+(3*1)+(2*4)+(1*6)=149
149 % 10 = 9
So 156571-46-9 is a valid CAS Registry Number.
InChI:InChI=1/C20H21N3O5/c1-3-22(4-2)14-6-5-13-11-15(20(27)28-16(13)12-14)19(26)21-9-10-23-17(24)7-8-18(23)25/h5-8,11-12H,3-4,9-10H2,1-2H3,(H,21,26)
156571-46-9Relevant articles and documents
Thiol-reactive Fluorescent probes for Protein Labelling
Corrie, John E. T.
, p. 2975 - 2982 (2007/10/02)
Cyclisation of N-alkylmaleic acids mediated by acetic anhydride in dimethylacetamide in the presence of traces of cobalt naphthenate has been used for efficient assembly of a range of fluorescent maleimide reagents.The fluorescence responses of these reagents to addition of thiol across the maleimide double bond, and to hydrolysis of the meleimide ring, are described.
