156604-79-4

Basic information

• Product Name: Dexketoprofen trometamol
• Synonyms: (s)-ketoprofen trometamol;dexketoprofen trometamol;2-amino-2-(hydroxymethyl)-1,3-propanediol (s)-3-benzoyl-alpha-methylbenzeneacetate;L-Ketoprofen trometamol;Dexketoprofen TroMetaMol API;2-AMino-2-(hydroxyMethyl)propane-1,3-diol (S)-2-(3-benzoylphenyl)propanoate;D-ketoprofen troMethaMine;(S)-Ketoprofen Tromethamine Salt (Dexketoprofen Trometamol)
• CAS NO: 156604-79-4
• Molecular Formula: C16H14O3.C4H11NO3
• Molecular Weight: 375.418
• EINECS: 1312995-182-4
• Product Categories: API;Other APIs
• Mol File: 156604-79-4.mol
• Article Data: 0

Chemical Properties

• Melting Point: 104.8-105.1°
• Boiling Point: 431.3 °C at 760 mmHg
• Flash Point: 228.8 °C
• Appearance: /
• Vapor Pressure: 3.32E-08mmHg at 25°C
• Storage Temp.: 2-8°C
• Solubility: DMSO, Ethanol (Slightly), Methanol (Sparingly)
• CAS DataBase Reference: Dexketoprofen trometamol(CAS DataBase Reference)
• NIST Chemistry Reference: Dexketoprofen trometamol(156604-79-4)
• EPA Substance Registry System: Dexketoprofen trometamol(156604-79-4)

Safety Data

• Hazardous Substances Data: 156604-79-4(Hazardous Substances Data)

Usage

Description

Dexketoprofen trometamol is a non-steroidal anti-inflammatory drug (NSAID) that possesses potent anti-inflammatory, analgesic, and antipyretic properties. It is derived from the parent drug, ketoprofen, and is formulated with trometamol to enhance its solubility and bioavailability. This medication is primarily used for the management of mild to moderate pain and is known for its rapid onset of action and minimal side effects.

Uses

Used in Pharmaceutical Industry:
Dexketoprofen trometamol is used as an analgesic for the treatment of mild to moderate pain. It is effective in alleviating various types of pain, including musculoskeletal pain, dysmenorrhea, dental pain, and other inflammatory conditions. The drug works by inhibiting the cyclooxygenase (COX) enzymes, which are responsible for the production of prostaglandins that cause inflammation, pain, and fever.
Used in Pain Management:
Dexketoprofen trometamol is used as a pain reliever for patients experiencing mild to moderate pain. Its rapid onset of action and long-lasting effects make it a suitable choice for managing acute and chronic pain conditions. It is particularly useful in cases where other NSAIDs may not be suitable due to side effects or contraindications.
Used in Inflammation Treatment:
Dexketoprofen trometamol is used as an anti-inflammatory agent for the treatment of various inflammatory conditions. It helps reduce inflammation by inhibiting the production of prostaglandins, which are responsible for the inflammatory response. This makes it an effective treatment option for conditions such as musculoskeletal pain, arthritis, and other inflammatory disorders.
Used in Dental Pain Management:
Dexketoprofen trometamol is used as a pain reliever for dental pain, including postoperative dental pain and toothache. Its potent analgesic properties and rapid onset of action make it an ideal choice for managing pain associated with dental procedures and conditions.
Used in Gynecological Pain Management:
Dexketoprofen trometamol is used as a pain reliever for dysmenorrhea, a condition characterized by painful menstrual cramps. Its anti-inflammatory and analgesic properties help alleviate the discomfort and pain associated with menstruation.

InChI:InChI=1/C16H14O3.C4H11NO3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12;5-4(1-6,2-7)3-8/h2-11H,1H3,(H,18,19);6-8H,1-3,5H2