1566470-05-0

Basic information

• Product Name: (E)-1-chloro-4-(3,3,3-trifluoro-1-phenylprop-1-en-2-yl)benzene
• Synonyms: (E)-1-chloro-4-(3,3,3-trifluoro-1-phenylprop-1-en-2-yl)benzene
• CAS NO: 1566470-05-0
• Molecular Weight: 282.693
• Mol File: 1566470-05-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-1-chloro-4-(3,3,3-trifluoro-1-phenylprop-1-en-2-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-chloro-4-(3,3,3-trifluoro-1-phenylprop-1-en-2-yl)benzene(1566470-05-0)
• EPA Substance Registry System: (E)-1-chloro-4-(3,3,3-trifluoro-1-phenylprop-1-en-2-yl)benzene(1566470-05-0)

Safety Data

• Hazardous Substances Data: 1566470-05-0(Hazardous Substances Data)

Upstream product

• 321-37-9 4'-chloro-2,2,2-trifluoroacetophenone 
• 1666-17-7 benzaldehyde p-toluenesulfonylhydrazone 
• 1023-17-2 4-methoxyphenyl benzyl ketone 
• 17151-48-3 tributyl(4-chlorophenyl)stannane 
• 72487-06-0 1-(4-chlorophenyl)-2,2,2-trifluoroethanol 

Relevant articles and documents

Synthesis of (Z)-α-Trifluoromethyl Alkenyl Triflate: A Scaffold for Diverse Trifluoromethylated Species

An efficient method for the synthesis of (Z)-selective α-trifluoromethyl alkenyl triflates is described. As an important fluorinated building block, it is utilized successfully for the synthesis of various trifluoromethyl derivatives such as diarylethylen

Copper(i)-catalyzed wittig olefination reactions of N-tosylhydrazones with trifluoromethylketones

Cuprous iodide-catalyzed Wittig olefination reactions of N-tosylhydrazones with trifluoromethylketones are reported. This procedure provides an efficient method for the synthesis of various trifluoromethyl-substituted alkenes in moderate to good yields (up to 89 % yield) and good stereoselectivity (up to 93 % E-selectivity). To the best of our knowledge, it is the first report of a Wittig reaction of N-tosylhydrazones with ketones. Copyright