156718-77-3Relevant articles and documents
Biosynthesis of (MWCNTs)-COOH/CdO hybrid as an effective catalyst in the synthesis of pyrimidine-thione derivatives by water lily flower extract
Kaveh, Shahrbano,Nami, Navabeh,Norouzi, Banafsheh,Mirabi, Ali
, p. 1459 - 1470 (2021)
Pink Water lily flower, with the scientific name of Nymphaea alba in the family of Nymphaeaceae, was collected from North of Iran, Mazandaran in spring, dried in shade and powdered. The powdered flower material was extracted in 70% (vol/vol) ethanol. Acid
COMPOUNDS HAVING PDE9A INHIBITORY ACTIVITY, AND PHARMACEUTICAL USES THEREOF
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Paragraph 0222, (2021/10/15)
The present invention provides a compound having a specific chemical structure and having PDE9A inhibitory activity, or a pharmaceutically acceptable salt thereof. The present invention provides a composition containing the compound or a pharmaceutically acceptable salt thereof. The present invention provides a pharmaceutical use, for treating or preventing PDE9A-related diseases, of the compound according to the present invention, a salt thereof, and a composition containing the compound or salt. The present invention also provides a method for treating or preventing PDE9A-related diseases, the method comprising administering an effective amount of the compound according to the present invention, a salt thereof, or a composition containing the compound or salt to a subject in need of treatment.
Microwave-assisted synthesis of substituted pyrazoles and pyrazolo [3,4-d]thiopyrimidines
Heravi, Majid M.,Nami, Navabeh,Seifi, Nasim,Oskooie, Hossein A.,Hekmatshoar, Rahim
, p. 591 - 599 (2007/10/03)
Ethyl(ethoxymethylene)cyanoacetate and ethoxymethylene malononitrile were synthesized from the reaction of malononitrile or ethylcyanoacetate with triethyl orthoformate or orthoacetate in N, N-dimethylacetamide under microwave irradiation. In a similar manner, substituted pyrazoles were synthesized from the reaction of ethyl (ethoxymethylene)cyanoacetate and ethoxymethylene malononitrile with phenylhydrazine. These pyrazoles were converted to pyrazolo[3,4-d]thiopyrimidines upon treatment with arylisothiocyanate and thiourea under microwave irradiation. Copyright Taylor & Francis Group, LLC.