15687-18-0 Usage
Description
Fenpentadiol, also known as 2-(4-chlorophenyl)-4-methylpentane-2,4-diol, is a pharmaceutical drug that possesses a range of therapeutic properties. It is characterized by its analgesic, antipyretic, and antihistaminic effects, making it a versatile compound for various medical applications.
Uses
Used in Pharmaceutical Industry:
Fenpentadiol is used as an analgesic for its pain-relieving properties, providing relief from mild to moderate pain.
Fenpentadiol is used as an antipyretic for its ability to reduce fever, helping to lower body temperature in cases of elevated heat due to illness.
Fenpentadiol is used as an antihistaminic for its effectiveness in counteracting the effects of histamine, which is responsible for symptoms such as itching, redness, and swelling in allergic reactions.
Additionally, fenpentadiol is used for the preventative or early treatment of inflammatory syndromes due to its ability to address the underlying causes of inflammation and alleviate associated symptoms.
Originator
Tredum,Heacutepatrol
Manufacturing Process
2-(p-Chlorophenyl)-4-methylpentane-2,4-diol (M.P. 76.5°C) was synthesized
and condensation of 2-(p-chlorophenyl)-3-hydroxybytiric acid ethyl ester with
CH3 MgI in ether.
Therapeutic Function
Antidepressant, Tranquilizer
Check Digit Verification of cas no
The CAS Registry Mumber 15687-18-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,6,8 and 7 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 15687-18:
(7*1)+(6*5)+(5*6)+(4*8)+(3*7)+(2*1)+(1*8)=130
130 % 10 = 0
So 15687-18-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H17ClO2/c1-11(2,14)8-12(3,15)9-4-6-10(13)7-5-9/h4-7,14-15H,8H2,1-3H3
15687-18-0Relevant articles and documents
Triflimide: An Overlooked High-Performance Catalyst of the Mukaiyama Aldol Reaction of Silyl Ketene Acetals with Ketones
Bae, Han Yong,List, Benjamin
, p. 13767 - 13772 (2018/09/12)
The Mukaiyama aldol reaction is a widely applied carbon–carbon bond forming reaction. However, despite numerous well-established methods using aldehydes as acceptors, only few examples exist with ketones. Here we report a highly practical catalytic approach to this transformation, namely, the triflimide catalyzed Mukaiyama aldol reaction of silyl ketene acetals with ketones. This method exhibits a broad substrate scope, is very rapid, tolerates functionalized substrates, and requires only parts-per-million catalyst loadings with preparative scale reactions up to hundreds of grams in excellent purity (>99 %).