157017-41-9

Basic information

• Product Name: 1H-Pyrrole, 1-(2-iodophenyl)-
• CAS NO: 157017-41-9
• Molecular Formula: C10H8IN
• Molecular Weight: 269.085
• Mol File: 157017-41-9.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole, 1-(2-iodophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole, 1-(2-iodophenyl)-(157017-41-9)
• EPA Substance Registry System: 1H-Pyrrole, 1-(2-iodophenyl)-(157017-41-9)

Safety Data

• Hazardous Substances Data: 157017-41-9(Hazardous Substances Data)

Usage

General Description

1H-Pyrrole, 1-(2-iodophenyl)- is a chemical compound with the molecular formula C10H8IN. It belongs to the class of pyrrole derivatives, which are aromatic heterocyclic compounds containing a five-membered ring with four carbon atoms and one nitrogen atom. The presence of the iodophenyl group in the molecule makes it useful for various applications in organic synthesis and pharmaceutical research. It is also commonly used as a reagent and building block in the production of complex organic molecules. The compound has been studied for its potential anti-cancer and anti-inflammatory properties, and it may have potential future applications in medicinal chemistry.

Upstream product

• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 615-43-0 2-iodophenylamine 
• 109-97-7 pyrrole 
• 615-42-9 1,2-Diiodobenzene 
• 635-90-5 1-phenylpyrrole 
• 332-77-4 2,5-dihydro-2,5-dimethoxyfuran 

Downstream Products

• 624739-92-0 4,5-diphenyl-pyrrolo[1,2-a]quinoline 
• 796843-23-7 1-(2-((trimethylsilyl)ethynyl)phenyl)-1H-pyrrole 
• 445262-79-3 1-(2-ethynylphenyl)-1H-pyrrole 

Relevant articles and documents

Synthesis of fluoren-9-ones by the palladium-catalyzed cyclocarbonylation of o-halobiaryls

The synthesis of various substituted fluoren-9-ones has been accomplished by the palladium-catalyzed cyclocarbonylation of o-halobiaryls. The cyclocarbonylation of 4′-substituted 2-iodobiphenyls produces very high yields of 2-substituted fluoren-9-ones bearing either electron-donating or electron-withdrawing substituents. 3′-Substituted 2-iodobiphenyls afford 3-substituted fluoren-9-ones in excellent yields with good regioselectivity. This chemistry has been successfully extended to polycyclic fluorenones and fluorenones containing fused isoquinoline, indole, pyrrole, thiophene, benzothiophene, and benzofuran rings.

Scalable electrochemical synthesis of diaryliodonium salts

Cyclic and acyclic diaryliodonium are synthesised by anodic oxidation of iodobiaryls and iodoarene/arene mixtures, respectively, in a simple undivided electrolysis cell in MeCN-HFIP-TfOH without any added electrolyte salts. This atom efficient process does not require chemical oxidants and generates no chemical waste. More than 30 cyclic and acyclic diaryliodonium salts with different substitution patterns were prepared in very good to excellent yields. The reaction was scaled-up to 10 mmol scale giving more than four grams of dibenzo[b,d]iodol-5-ium trifluoromethanesulfonate (>95%) in less than three hours. The solvent mixture of the large-scale experiment was recovered (>97%) and recycled several times without significant reduction in yield.

Synthesis of 1,3-Azaphospholes with Pyrrolo[1,2- a]quinoline Skeleton and Their Optical Applications

A facile synthesis of 1,3-azaphospholes with a pyrrolo[1,2-a]quinoline skeleton has been described. These new annulated 1,3-azaphospholes exhibit good photoelectric performance and can be used as the emitting dopant in organic light-emitting diodes (OLEDs) and dye for bioimaging.