1571067-17-8

Basic information

• Product Name: 1-(1,3-dioxoisoindolin-2-yl)-N-(quinolin-8-yl)cyclobutane-1-carboxamide
• Synonyms: 1-(1,3-dioxoisoindolin-2-yl)-N-(quinolin-8-yl)cyclobutane-1-carboxamide
• CAS NO: 1571067-17-8
• Molecular Weight: 371.395
• Mol File: 1571067-17-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(1,3-dioxoisoindolin-2-yl)-N-(quinolin-8-yl)cyclobutane-1-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1,3-dioxoisoindolin-2-yl)-N-(quinolin-8-yl)cyclobutane-1-carboxamide(1571067-17-8)
• EPA Substance Registry System: 1-(1,3-dioxoisoindolin-2-yl)-N-(quinolin-8-yl)cyclobutane-1-carboxamide(1571067-17-8)

Safety Data

• Hazardous Substances Data: 1571067-17-8(Hazardous Substances Data)

Upstream product

• 22264-50-2 1-aminocyclobutane-1-carboxylic acid 
• 85-44-9 phthalic anhydride 
• 1515815-56-1 1-amino-N-(quinolin-8-yl)cyclobutane-1-carboxamide 

Relevant articles and documents

Palladium-Catalyzed Decarbonylation of Amino Acid Derivatives via C-C Bond and C-N Bond Dual Activations

A unique decarbonylation of an amino acid derivative catalytic system has been established via palladium-catalyzed C-C bond and C-N bond dual activations. By employing 8-aminoquinoline as the directing group, this transformation has been found to facilitate the high chemoselectivity to decarbonylation of amino acid derivatives rather than intramolecular deamination or cross-dehydrogenative coupling reactions. This method provides a straightforward avenue for constructing diverse functionalized amide compounds in good to excellent yields. We proposed a possible reaction pathway that may go through the C-C bond and C-N bond dual activations on the basis of the mechanistic studies.