15725-45-8

Basic information

• Product Name: ethyl (E)-2-cyano-3-(4-cyanophenyl)-2-propenoate
• Synonyms: ethyl (E)-2-cyano-3-(4-cyanophenyl)-2-propenoate
• CAS NO: 15725-45-8
• Molecular Weight: 226.235
• Mol File: 15725-45-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: ethyl (E)-2-cyano-3-(4-cyanophenyl)-2-propenoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (E)-2-cyano-3-(4-cyanophenyl)-2-propenoate(15725-45-8)
• EPA Substance Registry System: ethyl (E)-2-cyano-3-(4-cyanophenyl)-2-propenoate(15725-45-8)

Safety Data

• Hazardous Substances Data: 15725-45-8(Hazardous Substances Data)

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 105-07-7 4-cyanobenzaldehyde 

Downstream Products

• 35802-05-2 ethyl 2-cyano-3-(4-cyanophenyl)oxirane-2-carboxylate 
• 52707-59-2 4-Cyanobenzaldoxime 

Relevant articles and documents

One-pot formation of functionalised 2-piperidinones from arylidenecyanoacetates and methanolic ammonia via tandem reactions

Aryl aldehydes react with ethyl cyanoacetate in methanolic ammonium acetate to expeditiously furnish, besides high yields of arylidenecyanoacetates, 4,6-diaryl-3,5-dicyano-5-ethoxycarbonyl-2-piperidinonesinlow yields. But preformed arylidenecyanoacetates

Hypervalent Iodine(III)-Catalyzed Epoxidation of β-Cyanostyrenes

A convenient approach for the synthesis of β-cyanoepoxides is illustrated by iodine(III)-catalyzed epoxidation of electron-deficient β-cyanostyrenes, wherein the active catalytic iodine(III) species was generated in situ. The epoxidation of β-cyanostyrenes was performed using 10 molpercent PhI as precatalyst in the presence of 2.0 equivalents Oxone as an oxidant and 2.4 equivalents of TFA as an additive at room temperature under ultrasonic radiations. The β-cyanoepoxides were isolated in good to excellent yields in a short reaction time.

Sodium carbonate: A versatile catalyst for Knoevenagel condensation

Catalytic amounts of sodium carbonate (Na2CO3) catalyze the condensation of aromatic aldehydes with active methylene compounds to afford arylmethylidene products under the grindstone method. The reactions go to completion within 1-5 min at 26°C and give products in excellent yield.