15731-72-3 Usage
Description
2'-Deoxyadenosine-3'-monophosphate, also known as 2''-Deoxy-3''-adenylic Acid, is a nucleotide derivative that plays a significant role in the study of single-stranded DNA damage. It is a 2'-deoxyadenosine phosphate with a monophosphate group located at the 3'-position, which makes it an essential component in various biological and pharmaceutical applications.
Uses
Used in Pharmaceutical Industry:
2'-Deoxyadenosine-3'-monophosphate is used as a research compound for studying the mechanisms of DNA damage and repair. Its application in this field is crucial for understanding the effects of various agents on single-stranded DNA and developing potential therapeutic strategies to counteract DNA damage.
Used in Biotechnology Industry:
In the biotechnology industry, 2'-Deoxyadenosine-3'-monophosphate is used as a building block for the synthesis of various nucleic acid-based molecules, such as oligonucleotides and modified nucleotides. These molecules have applications in gene therapy, molecular diagnostics, and the development of novel drugs targeting specific genetic disorders.
Used in Research and Development:
2'-Deoxyadenosine-3'-monophosphate is also used as a research tool in academic and industrial laboratories. It is employed in the study of DNA structure, function, and interactions with other biomolecules, such as proteins and enzymes. This knowledge is vital for advancing our understanding of genetic processes and the development of new therapeutic approaches for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 15731-72-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,7,3 and 1 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 15731-72:
(7*1)+(6*5)+(5*7)+(4*3)+(3*1)+(2*7)+(1*2)=103
103 % 10 = 3
So 15731-72-3 is a valid CAS Registry Number.
15731-72-3Relevant articles and documents
Resistance towards exonucleases of dinucleotides with stereochemically altered internucleotide phosphate bonds
Nair, Vasu,Pal, Suresh
, p. 289 - 291 (2007/10/03)
Kinetic constants for the hydrolytic susceptibility of the internucleotide phosphate bond in normal dinucleotides [e.g., 2′-deoxycytidylyl- (3′>5′)-2′-deoxyuridine (dCpdU) and 2′-deoxyadenylyl- (3′→5′)-2′-deoxycytidine (dApdC)] and isomeric dinucleotides