157335-97-2 Usage
Description
5-BROMO-4,6-DIMETHYLPYRIMIDINE is an organic compound that serves as a valuable synthetic intermediate in the field of chemical synthesis. It is characterized by its unique molecular structure, which includes a pyrimidine ring with a bromine atom at the 5th position and two methyl groups at the 4th and 6th positions. 5-BROMO-4,6-DIMETHYLPYRIMIDINE is known for its potential applications in various industries, particularly in the development of pharmaceuticals and other chemical products.
Uses
Used in Pharmaceutical Industry:
5-BROMO-4,6-DIMETHYLPYRIMIDINE is used as a synthetic intermediate for the preparation of indanyloxydihydrobenzofuranylacetic acids. These acids are known as GPR40 receptor modulators, which play a crucial role in the treatment of type 2 diabetes and other related metabolic disorders. The compound's unique structure allows for the development of new drugs that can effectively target and modulate the GPR40 receptor, leading to improved therapeutic outcomes for patients suffering from these conditions.
In addition to its application in the pharmaceutical industry, 5-BROMO-4,6-DIMETHYLPYRIMIDINE may also find use in other chemical synthesis processes, where its unique molecular structure can be leveraged to create novel compounds with potential applications in various fields. However, the specific uses in these industries may vary and would require further research and development to fully understand their potential benefits and limitations.
Check Digit Verification of cas no
The CAS Registry Mumber 157335-97-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,7,3,3 and 5 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 157335-97:
(8*1)+(7*5)+(6*7)+(5*3)+(4*3)+(3*5)+(2*9)+(1*7)=152
152 % 10 = 2
So 157335-97-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H7BrN2/c1-4-6(7)5(2)9-3-8-4/h3H,1-2H3
157335-97-2Relevant articles and documents
Synthesis and Proton NMR Spectra of the Monomethyl- and Dimethylpyrimidine-5-carboxylic Acids. Regioselective Covalent Hydration at the 2- and 4-Ring Positions
Kress, Thomas J.
, p. 1375 - 1382 (2007/10/02)
Pyrimidine-5-carboxylic acid, its 2-methyl, 4-methyl, 2,4-dimethyl- and 4,6-dimethyl derivatives have been synthesized and their proton nmr spectra measured in dilute aqueous acid.Pyrimidine-5-carboxylic acid (1a, R2,4,6=H) was found to afford an equilibrium mixture of covalent hydrates at both the 2- and 4-ring positions (2a and 3a).The 2-methyl derivative (1b, R2=Me, R4,6=H) undergoes hydration exclusively at the 4-position (2b) while the 4-methyl derivative (1c, R2,6=H, R4=Me) hydrates selectively at only the 2-position (3c).Covalent hydration was notobservable for either the 2,4-dimethyl- (1d, R2,4=Me, R6=H) or 4,6-dimethyl- (1e, R2=H, R4,6=Me) pyrimidinecarboxylic acids.The synthetic routes to these substances are described and the degree of hydration for each compound was measured.