157383-94-3

Basic information

• Product Name: 1-(4-chlorophenyl)-2-(4-fluorophenyl)-1,2-ethanedione
• Synonyms: 1-(4-chlorophenyl)-2-(4-fluorophenyl)-1,2-ethanedione
• CAS NO: 157383-94-3
• Molecular Weight: 262.668
• Mol File: 157383-94-3.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 1-(4-chlorophenyl)-2-(4-fluorophenyl)-1,2-ethanedione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorophenyl)-2-(4-fluorophenyl)-1,2-ethanedione(157383-94-3)
• EPA Substance Registry System: 1-(4-chlorophenyl)-2-(4-fluorophenyl)-1,2-ethanedione(157383-94-3)

Safety Data

• Hazardous Substances Data: 157383-94-3(Hazardous Substances Data)

Upstream product

• 39769-26-1 (E)-1-(4-fluorophenyl)-2-(4-chlorophenyl)ethene 
• 51477-13-5 (4-fluorophenyl)-3-(4-chlorophenyl)oxiran-2-yl-methanone 
• 25026-34-0 4-chlorophenacetyl chloride 
• 126866-16-8 2-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-ethanone 
• 64583-18-2 1-(para-chlorophenyl)-2-(para-fluorophenyl)acetylene 
• 3457-46-3 4,4'-dichlorobenzil 
• 1878-66-6 4-chlorophenylacetic Acid 

Relevant articles and documents

Copper/Iodine-Cocatalyzed C-C Cleavage of 1,3-Dicarbonyl Compounds Toward 1,2-Dicarbonyl Compounds

A new, general oxidative route to transformations of 1,3-dicarbonyl compounds to 1,2-dicarbonyl compounds by merging copper and I2 catalysis is described. This method is applicable to broad 1,3-dicarbonyl compounds, including 1,3-diketones, 1,3-keto esters and 1,3-keto amides. Mechanistical studies show that the reaction is achieved via the C–C bond cleavage and CO release cascades.

Method for synthesizing benzil derivatives

The invention discloses a method for synthesizing benzil derivatives. The method comprises the steps that a diphenyl acetylene compound, halogenated ammonium salt or iodine chloride and a sulfur source serve as reactants, the reactants react in a solvent for a period of time, purification is conducted, and then the benzil derivatives are obtained. According to the method, a metal catalyst and toxic iodine are not used, the applied reactants are low in price, poisonless and tasteless, the operation method is simple, the yield is high, aftertreatment is easy, and the method is suitable for industrial production.

A method for synthesizing derivatives benzil

The invention discloses a method for synthesizing a benzil derivative. The method comprises the following steps: adding epoxy chalcone compound shown in the formula I, a Selectfluor oxidizing agent and inorganic base into a mixed solvent of acetonitrile and water, stirring for reaction for 4-8 h at 60-100 DEG C, and treating a reaction liquid obtained after the reaction is finished to prepare the benzil derivative shown in the formula II. The synthesis method has the advantages that the raw materials are cheap and easy to obtain, transition metal catalysis is not needed, the oxygen source is easy to obtain and environment-friendly, the reaction condition is mild, the target substrate can be synthesized efficiently, the universality of the functional group is good, and the operation is simple and convenient.