1574215-15-8

Basic information

• Product Name: 5,5'-methylenebis(3-tert-butyl-4-hydroxybenzaldehyde)
• CAS NO: 1574215-15-8
• Molecular Weight: 368.473
• Mol File: 1574215-15-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5,5'-methylenebis(3-tert-butyl-4-hydroxybenzaldehyde)(CAS DataBase Reference)
• NIST Chemistry Reference: 5,5'-methylenebis(3-tert-butyl-4-hydroxybenzaldehyde)(1574215-15-8)
• EPA Substance Registry System: 5,5'-methylenebis(3-tert-butyl-4-hydroxybenzaldehyde)(1574215-15-8)

Safety Data

• Hazardous Substances Data: 1574215-15-8(Hazardous Substances Data)

Upstream product

• 119-47-1 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane 

Relevant articles and documents

Cu(OAc)2-catalyzed remote benzylic C(sp3)-H oxyfunctionalization for C=O formation directed by the hindered para-hydroxyl group with ambient air as the terminal oxidant under ligand- and additive-free conditions

A hindered para-hydroxyl group-directed remote benzylic C(sp3)-H oxyfunctionalization has been developed for the straightforward transformation of 2,6-disubstituted 4-cresols, 4-alkylphenols, 4-hydroxybenzyl alcohols and 4-hydroxybenzyl alkyl ethers into various aromatic carbonyl compounds. The ligand- and additive-free Cu(OAc)2-catalyzed atmospheric oxidation mediated by ethylene glycol unlocks a facile, atom-economical, and environmentally benign C=O formation for the functionalization of primary and secondary benzyl groups. Due to the pharmaceutical importance of 4-hydroxybenzaldehydes and 4-hydroxyphenones, the methodology is expected to be of significant value for both fundamental research and practical applications.