1575722-49-4

Basic information

• Product Name: 3-O-methyl-17-(4-methoxybenzyl )-β-estradiol
• Synonyms: 3-O-methyl-17-(4-methoxybenzyl )-β-estradiol
• CAS NO: 1575722-49-4
• Molecular Weight: 406.565
• Mol File: 1575722-49-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-O-methyl-17-(4-methoxybenzyl )-β-estradiol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-O-methyl-17-(4-methoxybenzyl )-β-estradiol(1575722-49-4)
• EPA Substance Registry System: 3-O-methyl-17-(4-methoxybenzyl )-β-estradiol(1575722-49-4)

Safety Data

• Hazardous Substances Data: 1575722-49-4(Hazardous Substances Data)

Upstream product

• 1035-77-4 3-O-methyl-17β-oestradiol 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 1035-77-4 3-O-methyl-17β-oestradiol 

Relevant articles and documents

Proton-exchanged montmorillonite-mediated reactions of methoxybenzyl esters and ethers

Proton-exchanged montmorillonite (H-mont) was found to be an eco-friendly and cost-effective catalyst for the generation of O-methylated quinone methides (QM) from the corresponding p or o-methoxybenzyl esters and ethers. Nucleophilic trapping of the O-methylated QM with arenes, alcohols, 1,3-dicarbonyl compounds, silyl enol ethers, and allylsilanes has been carried out, respectively, leading to eco-friendly benzylation reactions. Using this protocol, H-mont-mediated deprotection of PMB-protected esters and ethers have been realized for the first time. This work would pave the way for further exploration in O-alkylated QM that are of chemical and biological significance.