15760-26-6 Usage
Description
1-cyano-2-methylisothiourea, also known as Methylisothiourea (MITU), is a synthetic chemical compound with the molecular formula C3H6N4S. It is a potent inhibitor of nitric oxide synthase, an enzyme involved in the production of nitric oxide, a molecule that plays a key role in various physiological and pathological processes.
Uses
Used in Pharmaceutical Industry:
1-cyano-2-methylisothiourea is used as a therapeutic agent for the treatment of conditions such as septic shock, inflammation, and neurodegenerative diseases. Its ability to inhibit nitric oxide synthase makes it a potential candidate for managing the excessive production of nitric oxide, which can contribute to the severity of these conditions.
Used in Research Applications:
1-cyano-2-methylisothiourea is used as a research tool in scientific studies to investigate the role of nitric oxide in various physiological and pathological processes. By inhibiting nitric oxide synthase, researchers can gain insights into the mechanisms and effects of nitric oxide in different biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 15760-26-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,7,6 and 0 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 15760-26:
(7*1)+(6*5)+(5*7)+(4*6)+(3*0)+(2*2)+(1*6)=106
106 % 10 = 6
So 15760-26-6 is a valid CAS Registry Number.
15760-26-6Relevant articles and documents
Catalyst-free synthesis of thiazolidines: Via sequential hydrolysis/rearrangement reactions of 5-arylidenethiazolidin-4-ones at room temperature
Zeng, Fanxun,Zhang, Letian,Shao, Xusheng,Li, Zhong,Xu, Xiaoyong
supporting information, p. 1932 - 1938 (2018/03/23)
A catalyst-free sequential reaction involving hydrolysis and intramolecular aza-Michael addition was developed for synthesizing functionalized thiazolidines from 5-arylidenethiazolidin-4-ones at room temperature. A series of thiazolidine-5-carboxylic acids were prepared in good to excellent yields (up to 97% yield) and excellent diastereoselectivities (up to >20:1 dr). This methodology was applicable to the construction of derivatives of thiacloprid and flutianil with good yields.
