15798-77-3

Basic information

• Product Name: 8-methyl-2H-furo[2,3-h]chromen-2-one
• Synonyms: 2H-Furo(2,3-h)(1)benzopyran-2-one, 8-methyl-; 2H-Furo(2,3-h)-1-benzopyran-2-one, 8-methyl-; 2H-furo[2,3-h]-1-benzopyran-2-one, 8-methyl-; 8-Methyl-2H-furo(2,3-h)-1-benzopyran-2-one; 8-Methyl-2H-furo[2,3-h]chromen-2-one
• CAS NO: 15798-77-3
• Molecular Formula: C₁₂H₈O₃
• Molecular Weight: 200.1901
• Mol File: 15798-77-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 378.4°C at 760 mmHg
• Flash Point: 182.6°C
• Density: 1.332g/cm³
• Vapor Pressure: 6.31E-06mmHg at 25°C
• Refractive Index: 1.648
• CAS DataBase Reference: 8-methyl-2H-furo[2,3-h]chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-methyl-2H-furo[2,3-h]chromen-2-one(15798-77-3)
• EPA Substance Registry System: 8-methyl-2H-furo[2,3-h]chromen-2-one(15798-77-3)

Safety Data

• Hazardous Substances Data: 15798-77-3(Hazardous Substances Data)

Upstream product

• 67268-42-2 7-(propynyloxy)-2H-chromen-2-one 
• 64-17-5 ethanol 
• 860183-68-2 8-(iodomethyl)-8,9-dihydro-2H-furo[2,3-h]chromen-2-one 
• 55136-72-6 7-hydroxy-8-allylcoumarin 
• 93-35-6 7-hydroxy-2H-chromen-2-one 
• 377048-15-2 7-hydroxy-8-(2-methyl-2-propenyl)-2H-chromen-2-one 
• 314262-25-4 7-[(2-methyl-2-propenyl)oxy]-2H-chromen-2-one 
• 462094-54-8 2-[(2-oxo-2H-chromen-7-yl)oxy]propanal 
• 444109-47-1 7-hydroxy-8-(2-oxopropyl)-2H-chromen-2-one 
• 169135-31-3 4-(2-Chloro-allyloxy)-2-hydroxy-benzaldehyde 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 78560-55-1 7-acetoxy-8-(2',3'-dibromopropyl)coumarin 

Relevant articles and documents

Erratum: Efficient and short route for the regioselective synthesis of highly substituted, angularly fused furano-, pyrano-, and pyrrolocoumarin= quinolone derivatives by metal-mediated cyclization (Synthetic Communications (2010) 40:14 (2147-2157))

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Synthesis of thio- and oxo-analogues of isopsoralen

A range of novel 5′-substituted 7-oxo and 7-thioisopsoralens were synthesized via a Claisen rearranged allyl aryl ether followed by reductive ozonolysis in the presence of a suitable solvent. In some cases dimethylthiocarbamoyl chloride was used as a protecting group and to introduce the thiol moiety.

Microwave Promoted and Improved Thermal Synthesis of Pyranocoumarins and Furocoumarins

Propargyl ethers of 7-hydroxy-, 4-hydroxy-, and 4-methyl-7-hydroxycoumarins have been efficiently rearranged to pyranocoumarins and furocoumarins under microwave irradiation; improved thermal rearrangement of these ethers was also reported.