157982-31-5

Basic information

• Product Name: (R)-S-ethyl hydroxy-phenyl-thioacetate
• Synonyms: (R)-S-ethyl hydroxy-phenyl-thioacetate
• CAS NO: 157982-31-5
• Molecular Weight: 196.27
• Mol File: 157982-31-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-S-ethyl hydroxy-phenyl-thioacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-S-ethyl hydroxy-phenyl-thioacetate(157982-31-5)
• EPA Substance Registry System: (R)-S-ethyl hydroxy-phenyl-thioacetate(157982-31-5)

Safety Data

• Hazardous Substances Data: 157982-31-5(Hazardous Substances Data)

Upstream product

• 82027-28-9 S-ethyl 2-hydroxy-2-phenylethanethioate 
• 157982-25-7 (1R)-tetrahydropyran-(2RS)-2-yl [(1R,3R)-1-(1,3-dithiane-1,3-dioxide-2-yl)-1-phenyl]methyl ether 
• 158060-53-8 (1R,3R)-1,3-dithiane-1,3-dioxide-2-[(1R)-1-phenyl]methanol 
• 100-52-7 benzaldehyde 
• 157982-28-0 (1R)-S-ethyl [1-phenyl-1-tetrahydropyran-(2RS)-2-yloxy]-thioacetate 

Downstream Products

• 611-71-2 (R)-Mandelic Acid 

Relevant articles and documents

Asymmetrie aerobic oxidation of α-hydroxy acid derivatives by C 4-symmetric, vanadate-centered, tetrakisvanadyl(V) clusters derived from N-salicylidene-α-aminocarboxylates

(Chemical Equation Presented) A series of chiral vanadyl(V) methoxides bearing 3-t-butyl-5-substituted N-salicylene-L-valinate and L-t-leucinate as chiral auxiliaries has been prepared. In all cases except the 3,5-di-t-butyl analogue, they exist as monomers both in solution and in the single crystal state. In the case of the 3,5-di-t-butyl analogue, the architectural nature of the vanadyl(V) complex highly depends on the base used during the complex formation event. A pentanuclear C4-symmetric complex was formed when potassium salts were employed instead of the corresponding sodium salts. A central vanadate(V) unit serves to grip four identical chiral monomelic vanadyl(V) units together, by which a potassium ion sits on top of the four flanking units through carbonyl coordinations and serves to hold the whole cluster by cooperation with the central vanadate(V) unit. In comparison with the corresponding monomelic vanadyl(V) methoxide complex, the cluster complex was utilized to facilitate the asymmetric aerobic oxidations of various racemic α-hydroxyesters, -amides, and -thioesters with excellent selectivity factors (krel 40 to >500).

trans-1,3-Dithiane-1,3-Dioxide, a New Chiral Acyl Anion Equivalent for the Preparation of Masked Activated Acids: Application to the Synthesis of α-Hydroxy Acid Derivatives

trans-1,3-Dithiane-1,3-dioxide reacts with high diastereoselectivity with aromatic aldehydes and the 1,3-dithiane-1,3-dioxide moiety can be easily converted to a thiolester without racemisation by carrying out a Pummerer reaction; the thiolester is a group that can be readily transformed into acids, esters, amides, ketones and aldehydes.