158017-74-4

Basic information

• Product Name: 4-(7-Methoxy-benzo[1,3]dioxol-5-ylmethyl)-3-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-dihydro-furan-2-one
• CAS NO: 158017-74-4
• Molecular Weight: 428.439
• Mol File: 158017-74-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(7-Methoxy-benzo[1,3]dioxol-5-ylmethyl)-3-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-dihydro-furan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(7-Methoxy-benzo[1,3]dioxol-5-ylmethyl)-3-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-dihydro-furan-2-one(158017-74-4)
• EPA Substance Registry System: 4-(7-Methoxy-benzo[1,3]dioxol-5-ylmethyl)-3-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-dihydro-furan-2-one(158017-74-4)

Safety Data

• Hazardous Substances Data: 158017-74-4(Hazardous Substances Data)

Upstream product

• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 78173-82-7 3-(3-methoxy-4,5-methylenedioxybenzyl)butyrolactone 

Downstream Products

• 58546-54-6 6(SR),7(RS)-5,6,7,8-tetrahydro-7-hydroxy-1,10,11,12-tetramethoxy-6,7-dimethyl-2,3-methylenedioxydibenzocyclooctene 
• 143503-88-2 4-(3,4-Dihydroxy-5-methoxy-benzyl)-3-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-dihydro-furan-2-one 

Relevant articles and documents

Synthesis of optically pure gomisin A and schizandrin: The first total synthesis of gomisin A and schizandrin having naturally occurring configurations

The total synthesis of gomisin A and schizandrin having natural configurations were accomplished for the first time. The key feature of these syntheses is a highly efficient intramolecular oxidative coupling of the intermediates 9 and 21, which can be obtained as both enantiomers in optically pure forms. The manipulation of the lactone moieties of 7 and 22 afforded natural enantiomers of schizandrin and gomisin A.