1580507-02-3Relevant articles and documents
Targeting carnitine biosynthesis: Discovery of new inhibitors against γ-butyrobetaine hydroxylase
Tars, Kaspars,Leitans, Janis,Kazaks, Andris,Zelencova, Diana,Liepinsh, Edgars,Kuka, Janis,Makrecka, Marina,Lola, Daina,Andrianovs, Viktors,Gustina, Daina,Grinberga, Solveiga,Liepinsh, Edvards,Kalvinsh, Ivars,Dambrova, Maija,Loza, Einars,Pugovics, Osvalds
, p. 2213 - 2236 (2014)
γ-Butyrobetaine hydroxylase (BBOX) catalyzes the conversion of gamma butyrobetaine (GBB) to l-carnitine, which is involved in the generation of metabolic energy from long-chain fatty acids. BBOX inhibitor 3-(1,1,1-trimethylhydrazin-1-ium-2-yl)propanoate (