1581753-72-1

Basic information

• Product Name: (2-bromo-5-fluoro-4-nitro-phenyl)-acetic acid
• Synonyms: (2-bromo-5-fluoro-4-nitro-phenyl)-acetic acid
• CAS NO: 1581753-72-1
• Molecular Weight: 278.034
• Mol File: 1581753-72-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2-bromo-5-fluoro-4-nitro-phenyl)-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2-bromo-5-fluoro-4-nitro-phenyl)-acetic acid(1581753-72-1)
• EPA Substance Registry System: (2-bromo-5-fluoro-4-nitro-phenyl)-acetic acid(1581753-72-1)

Safety Data

• Hazardous Substances Data: 1581753-72-1(Hazardous Substances Data)

Upstream product

• 345-24-4 5-bromo-2,4-difluoronitrobenzene 
• 108-59-8 malonic acid dimethyl ester 

Relevant articles and documents

2-OXO-2,3-DIHYDRO-INDOLES FOR THE TREATMENT OF CNS DISORDERS

The present invention is concerned with 2-oxo-2,3-dihydro-indoles of general formula (I) wherein (N1) is phenyl or a heteroaryl group, selected from pyridinyl, pyrimidinyl, imidazolyl, isoxazolyl or pyrazolyl; (N2) is phenyl or pyridinyl, wherein the N atom in the pyridinyl group may be on all free positions; R1 is hydrogen, lower alkyl, lower alkyl substituted by halogen, lower alkoxy or halogen; n is 1 or 2; if n is 2, R1 may be the same or not; R2/R2' are independently from each other lower alkyl, or form together with the carbon atom to which they are attached a C3-6-cycloalkyl ring; R3 is lower alkyl, C3-6-cycloalkyl, CH2-C3-6-cycloalkyl, C3-6-cycloalkyl wherein one ring-carbon atom is replaced by -O-, (CH2)3-O-C3-6-cycloalkyl, lower alkyl substituted by hydroxy, lower alkyl substituted by halogen, (CH2)3-S(O)2-C3-6-cycloalkyl or (CH2)2-S(O)2-lower alkyl; R4 is hydrogen, halogen or lower alkyl; m is 1 or 2; if m is 2, R4 may be the same or not; as well as with a pharmaceutically acceptable salts thereof, with a racemic mixture, or with its corresponding enantiomer and/or optical isomer and/or stereoisomer thereof.