1582-01-0

Basic information

• Product Name: Phenol, 4-fluoro-, 4-methylbenzenesulfonate
• CAS NO: 1582-01-0
• Molecular Formula: C13H11FO3S
• Molecular Weight: 266.293
• Mol File: 1582-01-0.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Phenol, 4-fluoro-, 4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-fluoro-, 4-methylbenzenesulfonate(1582-01-0)
• EPA Substance Registry System: Phenol, 4-fluoro-, 4-methylbenzenesulfonate(1582-01-0)

Safety Data

• Hazardous Substances Data: 1582-01-0(Hazardous Substances Data)

Usage

General Description

Phenol, 4-fluoro-, 4-methylbenzenesulfonate is a chemical compound that consists of a phenol group with a 4-fluoro substitution and a 4-methylbenzenesulfonate group. Phenol, 4-fluoro-, 4-methylbenzenesulfonate is commonly used in organic synthesis and as a reagent in chemical reactions. It is also utilized in the production of pharmaceuticals, agrochemicals, and in the manufacturing of dyes and pigments. Phenol, 4-fluoro-, 4-methylbenzenesulfonate is known for its ability to form stable complexes with transition metals, making it a useful ligand in metal coordination chemistry. Its properties make it a valuable compound in various industrial processes and scientific research.

Upstream product

• 657-84-1 sodium tosylate 
• 371-41-5 4-Fluorophenol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 397-54-6 2-(4-fluorophenyl)benzoxazole 
• 1126639-46-0 4-n-butyl-5-(4-fluorophenyl)-1-phenyl-1H-1,2,3-triazole 
• 371-41-5 4-Fluorophenol 
• 28396-55-6 2-(4-fluorophenyl)naphthalene 
• 572-52-1 1-(4-fluorophenyl)naphthalene 
• 459-60-9 1-fluoro-4-methoxybenzene 
• 101493-80-5 p-fluorophenyl deuterated methyl ether 
• 2711-99-1 1-(4-fluorophenyl)-1-phenylhydrazine 
• 310-40-7 diethyl (4-fluorophenyl)phosphonate 
• 1516881-24-5 diisopropyl (4-fluorophenyl)phosphonate 
• 719-82-4 2-(4-fluorophenyl)-2-phenylacetonitrile 
• 39769-26-1 (E)-1-(4-fluorophenyl)-2-(4-chlorophenyl)ethene 
• 587-79-1 4-fluorodiphenylmethane 
• 345-83-5 4-fluorobenzophenone 

Relevant articles and documents

Palladium-catalyzed alkoxycarbonylation of aryl p-toluenesulfonate

Methyl- and ethyl arylcarboxylates were synthesized by palladium-catalyzed alkoxycarbonylation of various aryl p-toluenesulfonates (tosylates). Yields were highly dependent on the substituent of aryl tosylates and phosphine ligands used. Ethoxycarbonylation of 4-acetylphenyl tosylate by the use of a bisphosphine ligand gave ethyl 4-acetylbenzoate in quite satisfactory yields.

Palladium-Catalyzed Cyclobutanation of Aryl Sulfonates through both C-O and C-H Cleavage

A palladium-catalyzed cyclobutanation of aryl sulfonates with strained alkenes has been developed. The methodology is featured to achieve the cleavage of both C-O and C-H bonds of phenol derivatives in one pot. Under the reaction conditions, in addition t

Copper-Mediated Functionalization of Aryl Trifluoroborates

This paper describes the Cu(OTf)2-mediated coupling of aryl and heteroaryl trifluoroborates with tetrabutylammonium or alkali metal salts to form C-O, C-N, and C-halogen bonds. The reactions proceed under mild conditions (often room temperature over 16 hours) with carboxylate, halide, and azide salts, all nucleophiles that have been underrepresented in the copper cross-coupling literature. Preliminary results show that copper salts bearing weakly coordinating X-type ligands are essential for enabling these transformations to proceed under mild conditions.