158226-24-5

Basic information

• Product Name: α-5-(bromoethynyl)-1-<2-'deoxy-3',5'-di-O-(p-chlorobenzoyl)>-uridine
• Synonyms: α-5-(bromoethynyl)-1-<2-'deoxy-3',5'-di-O-(p-chlorobenzoyl)>-uridine
• CAS NO: 158226-24-5
• Molecular Weight: 608.229
• Mol File: 158226-24-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: α-5-(bromoethynyl)-1-<2-'deoxy-3',5'-di-O-(p-chlorobenzoyl)>-uridine(CAS DataBase Reference)
• NIST Chemistry Reference: α-5-(bromoethynyl)-1-<2-'deoxy-3',5'-di-O-(p-chlorobenzoyl)>-uridine(158226-24-5)
• EPA Substance Registry System: α-5-(bromoethynyl)-1-<2-'deoxy-3',5'-di-O-(p-chlorobenzoyl)>-uridine(158226-24-5)

Safety Data

• Hazardous Substances Data: 158226-24-5(Hazardous Substances Data)

Upstream product

• 23956-12-9 5-(2-hydroxyethyl)-uracil 
• 80184-05-0 1-chloro-2-deoxy-D-ribofuranose 
• 61135-31-7 5-(2,2-dibromovinyl)-uracil 
• 77530-00-8 5-(bromoethynyl)-uracil 
• 452-51-7 D-2-deoxyribose 
• 1195-08-0 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde 
• 3601-90-9 5-chloro-2-(((4-chlorobenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-chlorobenzoate 

Downstream Products

• 80384-36-7 5-(bromoethynyl)-α-2'-deoxyuridine 

Relevant articles and documents

Synthesis of a potential antiviral compound: 5-Bromoethynyl-2'- deoxyuridine

5-Bromoethynyluracil and its deoxyriboside can be prepared in good yields starting from dibromovinyluracil, which is accesible by literature methods. 5-Bromoethynyl-deoxyuridine is less effective against HSV-1 than E- (bromovinyl)-deoxyuridine but, similar to BVDU, seems to exhibit a certain selectivity toward HSV-1. Molecular calculations prove the spatial similarity of both compounds.