15846-25-0

Basic information

• Product Name: 3-aminocrotonamide
• Synonyms: 3-Aminocrotonamide,85%,tech.;2-Butenamide, 3-amino-;Einecs 239-956-0;3-AMino-but-2-enaMide;(Z)-3-aminobut-2-enamide
• CAS NO: 15846-25-0
• Molecular Formula: C₄H₈N₂O
• Molecular Weight: 100.12
• EINECS: 239-956-0
• Mol File: 15846-25-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 100-101 °C
• Boiling Point: 278.5°C at 760 mmHg
• Flash Point: 122.3°C
• Appearance: /
• Density: 1.082g/cm³
• Vapor Pressure: 0.00424mmHg at 25°C
• Refractive Index: 1.508
• PKA: 15.42±0.50(Predicted)
• CAS DataBase Reference: 3-aminocrotonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-aminocrotonamide(15846-25-0)
• EPA Substance Registry System: 3-aminocrotonamide(15846-25-0)

Safety Data

• Hazardous Substances Data: 15846-25-0(Hazardous Substances Data)

Usage

General Description

3-Aminocrotonamide is a chemical compound with the molecular formula C4H8N2O. It is a derivative of crotonamide and contains an amino group, making it an important building block in organic synthesis. 3-Aminocrotonamide is widely used in the pharmaceutical industry for the synthesis of various drugs and has been investigated for its potential therapeutic properties. It has also been used as a ligand in metal complexes and as a catalyst in organic reactions. Overall, 3-aminocrotonamide is a versatile and valuable chemical compound with a range of practical applications in various fields.

InChI:InChI=1/C4H8N2O/c1-3(5)2-4(6)7/h2H,5H2,1H3,(H2,6,7)/b3-2-

Upstream product

• 5977-14-0 acetoacetamido 
• 141-97-9 ethyl acetoacetate 
• 105-45-3 acetoacetic acid methyl ester 

Downstream Products

• 1360588-21-1 6-amino-4-methyl-5-[4-(methylphenyl)diazenyl]-2,2-diphenyl-3H-1,3,2λ⁴-oxazaborine 
• 86454-07-1 3,4-dihydro-6-methyl-4-oxo-2-pyrimidinepropanoic acid 
• 6622-92-0 2,6-dimethyl-1H-pyrimidin-4-one 
• 56951-00-9 ethyl 1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridinecarboxylate 
• 143755-55-9 5-Carbamoyl-2,6-dimethyl-4-phenyl-1,4-dihydro-pyridine-3-carboxylic acid ethyl ester 
• 86454-11-7 2-(3,4-dihydro-6-methyl-4-oxopyrimidin-2-yl)benzoic acid 
• 83726-89-0 6-methyl-2-(2'-methylthiazol-4'-yl)pyrimidin-4(3H)-one 
• 59341-68-3 6-methyl-2-(pyridin-4'-yl)pyrimidin-4(3H)-one 
• 55417-80-6 6-methyl-2-(pyridin-2'-yl)pyrimidin-4(3H)-one 

Relevant articles and documents

Synthesis and Characterization of New Boron Compounds Using Reaction of Diazonium Tetraphenylborate with Enaminoamides

A family of oxazaborines, diazaborinones, triazaborines, and triazaborinones was prepared by reaction of polarized ethylenes, such as β-enaminoamides, with 4-methylbenzenediazo-nium tetraphenylborates. The reaction conditions (stirring in CH2Cl2 at room temperature (Method A) or stirring with CH3COONa in CH2Cl2 at room temperature (Method B) or refluxing in the CH2Cl2/toluene mixture (Method C)) controlled the formation and relative content of these compounds in the reaction mixtures from one to three products. Substituted oxazaborines gradually rearranged into diazaborinones at 250 °C. The prepared compounds were characterized by1H NMR,13C NMR, IR, and UV–Vis spectroscopy, HRMS, or microanalysis. The structure of individual compounds was confirmed by11B NMR,15N NMR, 1D NOESY, and X-ray analysis. The mechanism of reaction of enaminoamides with 4-methylbenzenediazonium tetraphenylborate was proposed.