1584642-13-6

Basic information

• Product Name: 6-chloro-5-(4-(3-(dimethylamino)propoxy)-2,6-difluorophenyl)-2-(pyridin-2-yl)-N-(2,2,2-trifluoroethyl)pyrimidin-4-amine
• CAS NO: 1584642-13-6
• Molecular Weight: 501.887
• Mol File: 1584642-13-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-chloro-5-(4-(3-(dimethylamino)propoxy)-2,6-difluorophenyl)-2-(pyridin-2-yl)-N-(2,2,2-trifluoroethyl)pyrimidin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-5-(4-(3-(dimethylamino)propoxy)-2,6-difluorophenyl)-2-(pyridin-2-yl)-N-(2,2,2-trifluoroethyl)pyrimidin-4-amine(1584642-13-6)
• EPA Substance Registry System: 6-chloro-5-(4-(3-(dimethylamino)propoxy)-2,6-difluorophenyl)-2-(pyridin-2-yl)-N-(2,2,2-trifluoroethyl)pyrimidin-4-amine(1584642-13-6)

Safety Data

• Hazardous Substances Data: 1584642-13-6(Hazardous Substances Data)

Upstream product

• 585535-51-9 4,6-dichloro-2-(pyridin-2-yl)-5-(2,4,6-trifluorophenyl)pyrimidine 
• 585535-50-8 C₁₅H₈F₃N₃O₂ 
• 51285-26-8 pyridine-2-carboxamidine hydrochloride 
• 262609-07-4 diethyl (2,4,6-trifluoro-phenyl)-malonate 

Relevant articles and documents

Brain-penetrant, orally bioavailable microtubule-stabilizing small molecules are potential candidate therapeutics for Alzheimer's disease and related tauopathies

Microtubule (MT) stabilizing drugs hold promise as potential treatments for Alzheimer's disease (AD) and related tauopathies. However, thus far epothilone D has been the only brain-penetrant MT-stabilizer to be evaluated in tau transgenic mice and in AD p