158720-94-6

Basic information

• Product Name: 5-(4-chlorophenyl)-5-hydroxy-1-azaspiro[5.5]-undecane
• Synonyms: 5-(4-chlorophenyl)-5-hydroxy-1-azaspiro[5.5]-undecane
• CAS NO: 158720-94-6
• Molecular Weight: 279.81
• Mol File: 158720-94-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(4-chlorophenyl)-5-hydroxy-1-azaspiro[5.5]-undecane(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-chlorophenyl)-5-hydroxy-1-azaspiro[5.5]-undecane(158720-94-6)
• EPA Substance Registry System: 5-(4-chlorophenyl)-5-hydroxy-1-azaspiro[5.5]-undecane(158720-94-6)

Safety Data

• Hazardous Substances Data: 158720-94-6(Hazardous Substances Data)

Upstream product

• 158721-23-4 1-azaspiro[5.5]undecan-5-one 
• 89732-44-5 ethyl 1-(3-ethoxycarbonylpropylamino)cyclohexanecarboxylate 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 106-39-8 bromochlorobenzene 

Downstream Products

• 158720-69-5 5-(4-chlorophenyl)-1-azaspiro[5.5]undec-4-ene 
• 158720-68-4 5-(4-chlorophenyl)-1-ethyl-5-hydroxy-1-azaspiro[5.5]undecane hydrochloride 

Relevant articles and documents

Therapeutic agents

Compounds of formula I STR1 and pharmaceutically acceptable salts thereof in which m is an integer from 1 to 3; n is an integer from 2 to 6; R1 is phenyl optionally substituted by one or more substituents selected from halo, hydroxy, alkoxy, alkanoyl, alkyl, halogenated alkyl, alkylthio, alkylsulphinyl, alkylsulphonyl, cyano, nitro, optionally substituted amino, optionally substituted sulphamoyl, optionally substituted carbamoyl or phenyl, or R1 is naphthyl; R2 is H, alkyl or phenyl; R3 is H, alkyl, alkenyl or alkoxyalkyl; R4 is H or hydroxy; and R5 is H or together with R4 represents a bond; have utility in the treatment of obesity and affective disorders such as depression and anxiety.