15874-80-3

Basic information

• Product Name: Benzene, [(3-methyl-2-butenyl)sulfonyl]-
• CAS NO: 15874-80-3
• Molecular Formula: C11H14O2S
• Molecular Weight: 210.297
• Mol File: 15874-80-3.mol
• Article Data: 43

Chemical Properties

• CAS DataBase Reference: Benzene, [(3-methyl-2-butenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [(3-methyl-2-butenyl)sulfonyl]-(15874-80-3)
• EPA Substance Registry System: Benzene, [(3-methyl-2-butenyl)sulfonyl]-(15874-80-3)

Safety Data

• Hazardous Substances Data: 15874-80-3(Hazardous Substances Data)

Upstream product

• 873-55-2 sodium benzenesulfonate 
• 503-60-6 3,3-dimethyl-allyl chloride 
• 56069-39-7 diethyl phenylsulfonylmethylphosphonate 
• 78-84-2 isobutyraldehyde 
• 10276-04-7 3-methyl-1-phenylsulfanylbut-2-ene 
• 86031-23-4 C₁₁H₁₃BrO₂S 
• 84602-95-9 1-chloro-3-methyl-2-butenyl phenyl sulfone 
• 115-18-4 2-methyl-3-buten-2-ol 
• 541-28-6 isopentyl iodide 
• 123-51-3 i-Amyl alcohol 
• 16722-50-2 phenylsulphinate anion 
• 164513-96-6 1,1-dimethyl-2-propenyl isobutyl carbonate 
• 108-98-5 thiophenol 
• 24731-39-3 4-(phenylsulfonyl)butan-2-one 

Downstream Products

• 103904-63-8 4-Benzenesulfonyl-2-methyl-tridec-2-en-5-ol 
• 78828-39-4 3-(1-Benzenesulfonyl-3-methyl-but-2-enyl)-cyclohexanone 
• 84602-92-6 2-methyl-4,6-di(phenylsulphonyl)-2-hexene 
• 36971-12-7 1-(1,1-dimethylprop-2-en-1-yl)cyclohexan-1-ol 
• 64133-66-0 1-(3-methyl-2-butenyl)-1-cyclohexanol 
• 50465-67-3 (Z)-5-Benzenesulfonyl-3,7-dimethyl-octa-2,6-dien-1-ol 
• 50464-16-9 2,6-dimethyl-4-(phenylsulphonyl)-1,5-heptadiene 
• 181698-29-3 C₆H₅SO₂CH(Li)CHC(CH₃)2 
• 92643-37-3 2-methyl-5-phenyl-4-(phenylsulphonyl)-2-pentene 

Relevant articles and documents

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Development of a new air-stable structure-simplified nafuredin-γ analog as a potent and selective nematode complex I inhibitor

Nafuredin-γ, obtained from natural nafuredin, has demonstrated a potent and selective inhibitory activity against nematode complex I. However, nafuredin-γ is unstable in air since its conjugated dienes are oxygen-labile. The instability in air was natural

Synthesis of Sulfones and Sulfonyl Derivatives using Sodium (tert-butyldimethylsilyl)oxymethanesulfinate

The present invention relates to a method for manufacturing a sulfone and sulfonyl derivative compound using sodium (tert-butyldimethylsilyl)oxymethanesulfinate, which is a novel organic sulfin salt, wherein the novel organic sulfin salt has good stability, environmental friendliness and economy, and is easy to handle, and thus significantly reduces the amount of transition metal catalysts and the amount of organic sulfin salts used when introducing aryl or alkenyl. Also, alkylation, arylation, amination, and fluorination are all possible during secondary functionalization. Therefore, the present invention can be usefully used in preparation and mass production of various kinds of sulfones and derivatives thereof including asymmetric sulfone derivatives.

Silyloxymethanesulfinate as a sulfoxylate equivalent for the modular synthesis of sulfones and sulfonyl derivatives

An efficient protocol for the modular synthesis of sulfones and sulfonyl derivatives has been developed utilizing sodium tert-butyldimethylsilyloxymethanesulfinate (TBSOMS-Na) as a sulfoxylate (SO22-) equivalent. TBSOMS-Na, easily prepared from the commercial reagents Rongalite and TBSCl, serves as a potent nucleophile in S-alkylation and Cu-catalyzed S-arylation reactions with alkyl and aryl electrophiles. The sulfone products thus obtained can undergo the second bond formation at the sulfur center with various electrophiles without a separate unmasking step to afford sulfones and sulfonyl derivatives such as sulfonamides and sulfonyl fluorides.