1588418-79-4

Basic information

• Product Name: (4-((3-nitropyridin-2-yl)amino)phenyl)(1-(tetrahydro-2H-pyran-2-yl)-1H-benzo[d]imidazol-2-yl)methanone
• Synonyms: (4-((3-nitropyridin-2-yl)amino)phenyl)(1-(tetrahydro-2H-pyran-2-yl)-1H-benzo[d]imidazol-2-yl)methanone
• CAS NO: 1588418-79-4
• Molecular Weight: 443.462
• Mol File: 1588418-79-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-((3-nitropyridin-2-yl)amino)phenyl)(1-(tetrahydro-2H-pyran-2-yl)-1H-benzo[d]imidazol-2-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-((3-nitropyridin-2-yl)amino)phenyl)(1-(tetrahydro-2H-pyran-2-yl)-1H-benzo[d]imidazol-2-yl)methanone(1588418-79-4)
• EPA Substance Registry System: (4-((3-nitropyridin-2-yl)amino)phenyl)(1-(tetrahydro-2H-pyran-2-yl)-1H-benzo[d]imidazol-2-yl)methanone(1588418-79-4)

Safety Data

• Hazardous Substances Data: 1588418-79-4(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 4214-75-9 2-amino-3-nitropyridine 
• 1588418-78-3 (4-iodophenyl)(1-(tetrahydro-2H-pyran-2-yl)-1H-benzo[d]imidazol-2-yl)methanone 

Downstream Products

• 1588418-80-7 (4-((3-aminopyridin-2-yl)amino)phenyl)(1-(tetrahydro-2H-pyran-2-yl)-1H-benzo[d]imidazol-2-yl)methanone 

Relevant articles and documents

Discovery of novel imidazo[4,5- b ]pyridines as potent and selective inhibitors of phosphodiesterase 10A (PDE10A)

We report the discovery of novel imidazo[4,5-b]pyridines as potent and selective inhibitors of PDE10A. The investigation began with our recently disclosed ketobenzimidazole 1, which exhibited single digit nanomolar PDE10A activity but poor oral bioavailab