158894-41-8Relevant articles and documents
Stereoisomers of cyclic urea HIV-1 protease inhibitors: Synthesis and binding affinities
Kaltenbach III,Nugiel,Lam,Klabe,Seitz
, p. 5113 - 5117 (2007/10/03)
We have synthesized stereoisomers of cyclic urea HIV-1 protease inhibitors to study the effect of varying configurations on binding affinities. Four different synthetic approaches were used to prepare the desired cyclic urea stereoisomers. The original cy