158966-44-0 Usage
Description
3',5'-DI-O-BENZOYL-5-FLUORO-2'-O-METHYLURIDINE is a derivative of 6-Methyluridine (M338165), characterized by its unique chemical structure and properties. It is a compound that has demonstrated potential in various applications, particularly in the field of pharmaceuticals and biochemistry.
Uses
Used in Antimalarial Applications:
3',5'-DI-O-BENZOYL-5-FLUORO-2'-O-METHYLURIDINE is used as an antimalarial agent for its weak activity against P. falciparum 3D7 isolate. 3',5'-DI-O-BENZOYL-5-FLUORO-2'-O-METHYLURIDINE has shown promise in the development of new treatments for malaria, a disease that affects millions of people worldwide.
Used in Biochemical Research:
In the field of biochemistry, 3',5'-DI-O-BENZOYL-5-FLUORO-2'-O-METHYLURIDINE is used as a weak substrate of Escherichia coli pyrimidine nucleoside phosphorylase. This application allows researchers to study the enzyme's activity and its role in various biological processes, contributing to a better understanding of cellular functions and the development of targeted therapies.
Used in Pharmaceutical Industry:
3',5'-DI-O-BENZOYL-5-FLUORO-2'-O-METHYLURIDINE is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and properties make it a valuable building block for the development of new drugs, particularly those targeting infectious diseases and other medical conditions.
Used in Drug Design and Development:
The compound's properties also make it a useful tool in drug design and development. Researchers can utilize 3',5'-DI-O-BENZOYL-5-FLUORO-2'-O-METHYLURIDINE to create novel drug candidates with improved efficacy, safety, and pharmacokinetic profiles, ultimately leading to more effective treatments for patients.
Check Digit Verification of cas no
The CAS Registry Mumber 158966-44-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,8,9,6 and 6 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 158966-44:
(8*1)+(7*5)+(6*8)+(5*9)+(4*6)+(3*6)+(2*4)+(1*4)=190
190 % 10 = 0
So 158966-44-0 is a valid CAS Registry Number.
158966-44-0Relevant articles and documents
Apparatus and processes for the large scale generation and transfer of diazomethane
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, (2008/06/13)
For large scale preparation of pyrimidine ribonucleosides, the intermediate 2-O-methyl-(or ethyl)-1,3,5-tri-O-benzoyl-α-D-ribose can be prepared using a diazomethane (or diazoethane) reaction that is controlled via an inert solvent transferring system. This transfer system allows for large scale preparations of the pyrimidine ribonucleosides.