159006-07-2

Basic information

• Product Name: 2S-[[(dimethylamino)acetyl]amino]-N-[2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)propyl]-3,3-dimethylbutanamide
• Synonyms: 2S-[[(dimethylamino)acetyl]amino]-N-[2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)propyl]-3,3-dimethylbutanamide
• CAS NO: 159006-07-2
• Molecular Weight: 526.741
• Mol File: 159006-07-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2S-[[(dimethylamino)acetyl]amino]-N-[2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)propyl]-3,3-dimethylbutanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2S-[[(dimethylamino)acetyl]amino]-N-[2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)propyl]-3,3-dimethylbutanamide(159006-07-2)
• EPA Substance Registry System: 2S-[[(dimethylamino)acetyl]amino]-N-[2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)propyl]-3,3-dimethylbutanamide(159006-07-2)

Safety Data

• Hazardous Substances Data: 159006-07-2(Hazardous Substances Data)

Upstream product

• 62965-10-0 (S)-N-carbobenzoxy-tert-butylleucine 
• 2592-95-2 benzotriazol-1-ol 

Downstream Products

• 169437-02-9 2S-[[(dimethylamino)acetyl]amino]-N-[2R-hydroxy-3-[(3-methyl-butyl)(phenylsulfonyl)amino]-1S-(phenylmethyl)propyl]-3,3-dimethylbutaneamide 
• 159005-93-3 2S-[[(dimethylamino)-acetyl] amino]-N-[2R-hydroxy-3-[(3-methylbutyl)-(phenylsulfonyl)amino]-1S-(phenylmethyl) propyl]-3,3-dimethylbutaneamide 

Relevant articles and documents

α-and β-amino acid hydroxyethlamino sulfonamides useful as retroviral protease inhibitors

α- and β-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.

Hydroxyethylamino sulphonamides useful as retroviral protease inhibitors

PCT No. PCT/US94/09139 Sec. 371 Date Jan. 24, 1996 Sec. 102(e) Date Jan. 24, 1996 PCT Filed Aug. 23, 1994 PCT Pub. No. WO95/06030 PCT Pub. Date Mar. 2, 1995The invention relates to sulfonamide-containing hydroxyethylamine protease inhibitor compounds, their process of making, composition and method of use for inhibiting retroviral proteases such as human immunodeficiency virus.

β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors

α- and β-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.