159256-61-8

Basic information

• Product Name: 6-α-carbamoylpropylthio-4-mercapto-1-phenylpyrazolo[3,4-d]pyrimidine
• Synonyms: 6-α-carbamoylpropylthio-4-mercapto-1-phenylpyrazolo[3,4-d]pyrimidine
• CAS NO: 159256-61-8
• Molecular Weight: 345.449
• Mol File: 159256-61-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-α-carbamoylpropylthio-4-mercapto-1-phenylpyrazolo[3,4-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-α-carbamoylpropylthio-4-mercapto-1-phenylpyrazolo[3,4-d]pyrimidine(159256-61-8)
• EPA Substance Registry System: 6-α-carbamoylpropylthio-4-mercapto-1-phenylpyrazolo[3,4-d]pyrimidine(159256-61-8)

Safety Data

• Hazardous Substances Data: 159256-61-8(Hazardous Substances Data)

Upstream product

• 6289-02-7 1-phenylpyrazolo<3,4-d>pyrimidine-4,6(5H,7H)-dithione 
• 5398-24-3 2-bromobutyramide 
• 6289-02-7 1-phenyl-5H,7H-pyrazolo<3,4-d>pyrimidine-4,6-dithione 

Downstream Products

• 181702-35-2 2-(4-Methylsulfanyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-butyramide 

Relevant articles and documents

Pyrazolo[3,4-d]pyrimidines: C4, C6 substitution leads to adenosine A1 receptor selectivity

Following the demonstration that substitution of 1-phenylpyrazolo[3,4-d]pyrimidines at C6 with thioethers containing amide moieties could effect adenosine A1 and A(2a) receptor selectivity, two compounds with high A1 selectivity have been obtained by a combined C4, C6 substitution. This further demonstrates that distal moieties at C6 can effect selectivity and that C4 substituents have an important role.

Pyrazolo[3,4-d]pyrimidines with adenosine-like binding affinities

The A21 receptor extracelluar site and the A2 receptor extracellular site of adenosine analogues are structurally different and that binding orientations of adenosine or adenosine analogues are different at these sites and this may be used to determine th