15929-43-8

Basic information

• Product Name: bis(4-(trifluoroMethyl)phenyl)phosphine oxide
• Synonyms: bis(4-(trifluoroMethyl)phenyl)phosphine oxide
• CAS NO: 15929-43-8
• Molecular Formula: C₁₄H₉F₆OP
• Molecular Weight: 338.1848402
• Mol File: 15929-43-8.mol
• Article Data: 13

Chemical Properties

• Melting Point: 67-69 °C
• Boiling Point: 336.4±52.0 °C(Predicted)
• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: bis(4-(trifluoroMethyl)phenyl)phosphine oxide(CAS DataBase Reference)
• NIST Chemistry Reference: bis(4-(trifluoroMethyl)phenyl)phosphine oxide(15929-43-8)
• EPA Substance Registry System: bis(4-(trifluoroMethyl)phenyl)phosphine oxide(15929-43-8)

Safety Data

• Hazardous Substances Data: 15929-43-8(Hazardous Substances Data)

Usage

General Description

Bis(4-(trifluoromethyl)phenyl)phosphine oxide is a chemical compound with the molecular formula C14H9F6OP. It is a white to off-white crystalline solid. bis(4-(trifluoroMethyl)phenyl)phosphine oxide is commonly used as a photoinitiator for the curing of coating materials, adhesives, and inks. Additionally, it is used in the manufacturing of polymers and as a stabilizer in plastics. Bis(4-(trifluoromethyl)phenyl)phosphine oxide is known for its high thermal stability and ability to efficiently initiate photochemical reactions, making it a valuable and versatile compound in various industrial applications. However, it should be handled with caution and proper safety measures, as it can be hazardous if not used properly.

Upstream product

• 13685-91-1 (diethylamino)bis(4-trifluoromethylphenyl)phosphane 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 402-51-7 4-(trifluoromethyl)phenylmagnesium bromide 
• 762-04-9 phosphonic acid diethyl ester 
• 13406-27-4 tris(4-trifluoromethylphenyl)phosphine oxide 
• 13685-24-0 bis(4-trifluoromethylphenyl)phosphine chloride 
• 762-04-9 Diethyl phosphonate 

Downstream Products

• 98507-89-2 (PrCl₃((CF₃C₆H₄)2PHO)3) 
• 99665-68-6 potassium bis(4-(trifluoromethyl)phenyl)phosphide 
• 1255859-74-5 (S)-2-(2-(bis(4-trifluoromethyl-phenyl)phosphoryl))-5-(4-trifluoromethyl-phenyl)-4-tert-butyl-4,5-dihydro-oxazole 
• 1255859-78-9 C₃₉H₃₂F₆NO₂P 
• 1315513-21-3 (CF₃C₆H₄)2PCH₂CH(OCH₂CH₃)2 
• 1372559-65-3 phenylbis(4-(trifluoromethyl)phenyl)phosphine oxide 
• 282536-67-8 (R)-(+)-2-(bis(4-trifluoromethylphenyl)phosphinyl)-2'-methoxy-1,1'-binaphthyl 
• 13685-24-0 bis(4-trifluoromethylphenyl)phosphine chloride 
• 15929-46-1 Bis-(p-trifluormethyl-phenyl)-thiolphosphinsaeure-phenylester 

Relevant articles and documents

The organocatalytic enantiodivergent fluorination of β-ketodiaryl-phosphine oxides for the construction of carbon-fluorine quaternary stereocenters

Commercially available cinchona alkaloids that can catalyze the enantiodivergent fluorination of β-ketodiarylphosphine oxides were developed to construct carbon-fluorine quaternary stereocenters. This protocol features a wide scope of substrates and excellent enantioselectivities, and it is scalable.

B(C6F5)3-catalyzed O-H insertion reactions of diazoalkanes with phosphinic acids

A highly efficient base-, metal-, and oxidant-free catalytic O-H insertion reaction of diazoalkanes and phosphinic acids in the presence of B(C6F5)3has been developed. This powerful methodology provides a green approach towards the synthesis of a broad spectrum of α-phosphoryloxy carbonyl compounds with good to excellent yields (up to 99% yield). The protocol features the advantages of operational simplicity, high atom economy, practicality, easy scalability and environmental friendliness.

Highly chemo- and regioselective C-P cross-coupling reaction of quinone imine ketals with Ar2P(O)H to construct: Ortho -amino triarylphosphine derivatives

A highly chemo- and regioselective approach for the construction of ortho-amino triarylphosphine oxides has been achieved through a C-P cross-coupling reaction involving quinone imine ketals (QIKs) with Ar2P(O)H and catalyzed via a Lewis base. This alternative protocol provided a wide substrate scope with excellent yields (82-95%), and a variety of ortho-amino triarylphosphines were obtained with high yields (87-95%) via further reductive reaction. Furthermore, this reaction could be scaled-up and several synthetic transformations were accomplished for the construction of functionalized organophosphorus.