15931-15-4 Usage
Description
3-Fluoro-2-methylpyridine is an organic compound with the molecular formula C6H6FN. It is a derivative of pyridine, featuring a fluorine atom at the 3rd position and a methyl group at the 2nd position. 3-FLUORO-2-METHYLPYRIDINE is known for its potential applications in various chemical and pharmaceutical processes due to its unique structural properties.
Uses
Used in Pharmaceutical Industry:
3-Fluoro-2-methylpyridine is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with improved properties and efficacy.
Used in Synthesis of Fluorine-Containing Pyridinealdoximes:
3-Fluoro-2-methylpyridine is used as a starting material for the synthesis of fluorine-containing pyridinealdoximes, which have potential applications in the reactivation of cholinesterase. Cholinesterase reactivation is crucial in the treatment of poisoning caused by organophosphates and carbamates, which are commonly used as pesticides and nerve agents.
Check Digit Verification of cas no
The CAS Registry Mumber 15931-15-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,9,3 and 1 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 15931-15:
(7*1)+(6*5)+(5*9)+(4*3)+(3*1)+(2*1)+(1*5)=104
104 % 10 = 4
So 15931-15-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H6FN/c1-5-6(7)3-2-4-8-5/h2-4H,1H3
15931-15-4Relevant articles and documents
Expanding the Balz–Schiemann Reaction: Organotrifluoroborates Serve as Competent Sources of Fluoride Ion for Fluoro-Dediazoniation
Mohy El Dine, Tharwat,Sadek, Omar,Gras, Emmanuel,Perrin, David M.
supporting information, p. 14933 - 14937 (2018/09/25)
The Balz–Schiemann reaction endures as a method for the preparation of (hetero)aryl fluorides yet is eschewed due to the need for harsh conditions or high temperatures along with the need to isolate potentially explosive diazonium salts. In a departure from these conditions, we show that various organotrifluoroborates (RBF3?s) may serve as fluoride ion sources for solution-phase fluoro-dediazoniation in organic solvents under mild conditions. This methodology was successfully extended to a one-pot process obviating aryl diazonium salt isolation. Sterically hindered (hetero)anilines are fluorinated under unprecedentedly mild conditions in good-to-excellent yields. Taken together, this work expands the repertoire of RBF3?s to act as fluorine ion sources in an update to the classic Balz–Schiemann reaction.
