1596-67-4 Usage
Description
L-Thyronine, also known as thyroxine or T4, is a primary thyroid hormone derived from amino acids found in the human body. It is a slightly yellow powder and plays a crucial role in various physiological processes. L-Thyronine is essential for regulating growth and maturation before birth in mammals, as well as maintaining overall metabolic homeostasis.
Uses
Used in Pharmaceutical Industry:
L-Thyronine is used as a medication for treating hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormones. It helps in regulating the body's metabolism and ensuring proper growth and development.
Used in Veterinary Medicine:
In the veterinary field, L-Thyronine is used to treat thyroid-related disorders in animals, such as hypothyroidism and goiter. It helps in maintaining the overall health and well-being of the animals by regulating their metabolic processes.
Used in Research and Development:
L-Thyronine is also used in research and development for studying the effects of thyroid hormones on various biological processes, including growth, development, and metabolism. This helps in understanding the underlying mechanisms of thyroid hormone action and developing new therapeutic strategies for related disorders.
Used in Nutritional Supplements:
L-Thyronine is sometimes used as an ingredient in nutritional supplements, particularly for individuals with thyroid-related issues or those looking to support their overall metabolic health. However, it is essential to consult a healthcare professional before using such supplements, as improper use can lead to adverse effects.
Check Digit Verification of cas no
The CAS Registry Mumber 1596-67-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,9 and 6 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1596-67:
(6*1)+(5*5)+(4*9)+(3*6)+(2*6)+(1*7)=104
104 % 10 = 4
So 1596-67-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H15NO4/c16-14(15(18)19)9-10-1-5-12(6-2-10)20-13-7-3-11(17)4-8-13/h1-8,14,17H,9,16H2,(H,18,19)
1596-67-4Relevant articles and documents
Remarkable Effect of Chalcogen Substitution on an Enzyme Mimetic for Deiodination of Thyroid Hormones
Raja, Karuppusamy,Mugesh, Govindasamy
supporting information, p. 7674 - 7678 (2015/06/25)
Iodothyronine deiodinases are selenoenzymes which regulate the thyroid hormone homeostasis by catalyzing the regioselective deiodination of thyroxine (T4). Synthetic deiodinase mimetics are important not only to understand the mechanism of enzyme catalysis, but also to develop therapeutic agents as abnormal thyroid hormone levels have implications in different diseases, such as hypoxia, myocardial infarction, critical illness, neuronal ischemia, tissue injury, and cancer. Described herein is that the replacement of sulfur/selenium atoms in a series of deiodinase mimetics by tellurium remarkably alters the reactivity as well as regioselectivity toward T4. The tellurium compounds reported in this paper represent the first examples of deiodinase mimetics which mediate sequential deiodination of T4 to produce all the hormone derivatives including T0 under physiologically relevant conditions.
