159645-66-6

Basic information

• Product Name: Butanoic acid, 4-(4-amino-2,6-dimethoxyphenoxy)-, methyl ester
• Synonyms: Methyl 4-(4-amino-2,6-dimethoxy-phenoxy)butanoate;4-(4-Amino-2,6-dimethoxy-phenoxy)-butyric acid methyl ester
• CAS NO: 159645-66-6
• Molecular Formula: C₁₃H₁₉NO₅
• Molecular Weight: 269.29
• Mol File: 159645-66-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 418.049 °C at 760 mmHg
• Flash Point: 184.758 °C
• Density: 1.155 g/cm³
• CAS DataBase Reference: Butanoic acid, 4-(4-amino-2,6-dimethoxyphenoxy)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 4-(4-amino-2,6-dimethoxyphenoxy)-, methyl ester(159645-66-6)
• EPA Substance Registry System: Butanoic acid, 4-(4-amino-2,6-dimethoxyphenoxy)-, methyl ester(159645-66-6)

Safety Data

• Hazardous Substances Data: 159645-66-6(Hazardous Substances Data)

Upstream product

• 1136-86-3 methyl (3,4,5-trimethoxyphenyl) ketone 
• 159645-64-4 4-(4-Acetyl-2,6-dimethoxy-phenoxy)-butyric acid methyl ester 
• 2478-38-8 1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone 
• 6307-90-0 3,4,5-trimethoxy-1-nitrobenzene 
• 4897-84-1 Methyl 4-bromobutyrate 
• 205868-62-8 4-(2,6-Dimethoxy-4-nitro-phenoxy)-butyric acid methyl ester 
• 159645-65-5 4-(4-Acetylamino-2,6-dimethoxy-phenoxy)-butyric acid methyl ester 

Downstream Products

• 205868-64-0 4-[4-(2,4-Dinitro-phenylamino)-2,6-dimethoxy-phenoxy]-butyric acid 
• 205868-63-9 4-[4-(2,4-Dinitro-phenylamino)-2,6-dimethoxy-phenoxy]-butyric acid methyl ester 

Relevant articles and documents

Studies of a novel biomimetic radical spirocyclisation

The mechanism of the radical spirocyclisation 7→9 has been investigated. It has been shown by isotopic labelling that the biaryl ether oxygen does not emerge as the carbonyl group oxygen in the product, nor does the latter arise by hydrolysis of an intermediate e.g. 33 by added water. The mechanism of Scheme 1 path a is proposed, involving oxygen transfer from an aromatic nitro group to carbon in a cyclohexadienyl radical. Radical decarboxylation of the biarylamine derivative 29 does not lead to spirodienone 9 but diverts instead to the azathiaacetal 30.