1597438-90-8

Basic information

• Product Name: 4,7,7-trimethyl-4-phenyl-3-(trifluoromethyl)-6,7,8,9-tetrahydro-2H-pyrazolo[3,4-b]quinolin-5(4H)-one
• CAS NO: 1597438-90-8
• Molecular Weight: 375.394
• Mol File: 1597438-90-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,7,7-trimethyl-4-phenyl-3-(trifluoromethyl)-6,7,8,9-tetrahydro-2H-pyrazolo[3,4-b]quinolin-5(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4,7,7-trimethyl-4-phenyl-3-(trifluoromethyl)-6,7,8,9-tetrahydro-2H-pyrazolo[3,4-b]quinolin-5(4H)-one(1597438-90-8)
• EPA Substance Registry System: 4,7,7-trimethyl-4-phenyl-3-(trifluoromethyl)-6,7,8,9-tetrahydro-2H-pyrazolo[3,4-b]quinolin-5(4H)-one(1597438-90-8)

Safety Data

• Hazardous Substances Data: 1597438-90-8(Hazardous Substances Data)

Upstream product

• 852443-61-9 5-amino-3-(trifluoromethyl)-1H-pyrazole 
• 126-81-8 dimedone 
• 98-86-2 acetophenone 

Relevant articles and documents

KINASE INHIBITORS AND METHODS OF USE THEREOF

The present invention provides compounds of formula I, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting kinase (e.g., GSK3 (e.g., GSK3α or GSK3β) or CK1) activity. The present invention further provides methods of using the compounds described herein for treating kinase-mediated disorders, such as neurological diseases, psychriatic disorders, metabolic disorders, and cancer.