159782-26-0

Basic information

• Product Name: Benzamide, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxy-
• CAS NO: 159782-26-0
• Molecular Formula: C17H16Cl2N2O3
• Molecular Weight: 367.232
• Mol File: 159782-26-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzamide, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxy-(159782-26-0)
• EPA Substance Registry System: Benzamide, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxy-(159782-26-0)

Safety Data

• Hazardous Substances Data: 159782-26-0(Hazardous Substances Data)

Upstream product

• 22002-44-4 2-chloro-1-methoxy-4-methylbenzene 
• 144036-24-8 3-hydroxy-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide 
• 2516-33-8 Cyclopropylmethanol 

Downstream Products

• 162401-32-3 roflumilast 

Relevant articles and documents

Preparation methods of anti-inflammatory agent roflumilast for inhibiting PDE4 enzymatic activity and intermediate of roflumilast

The invention discloses preparation methods of an anti-inflammatory agent roflumilast for inhibiting the PDE4 enzymatic activity and an intermediate of the roflumilast. A chemical name of the anti-inflammatory agent roflumilast for inhibiting the PDE4 enzymatic activity is 3-(cyclopropyl methoxy)-N-(3,3-dichloropyridine-4-yl)-4-(difluoromethoxy) benzamide, the chemical formula of the roflumilast is C17H14C12F2N2O3, and the structural formula of the roflumilast is described as follow: (the structural formula is shown in the description). The preparation methods are concise in preparation technological process, available in raw material, simple in synthetic condition and high in yield and purity of a product, is environmentally friendly, is beneficial to realizing industrialization, lowers the production cost and is suitable for mass production; and the searched novel preparation methods of the roflumilast and the intermediate thereof have great significance on economical technology of the roflumilast.