159885-60-6

Basic information

• Product Name: 2-<4-carboethoxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole
• Synonyms: 2-<4-carboethoxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole
• CAS NO: 159885-60-6
• Molecular Weight: 435.35
• Mol File: 159885-60-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-<4-carboethoxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-<4-carboethoxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole(159885-60-6)
• EPA Substance Registry System: 2-<4-carboethoxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole(159885-60-6)

Safety Data

• Hazardous Substances Data: 159885-60-6(Hazardous Substances Data)

Upstream product

• 79-19-6 thiosemicarbazide 
• 1048670-08-1 2-[1-ethoxy-meth-(Z)-ylidene]-4,4,4-trifluoro-3-oxo-butyric acid ethyl ester 
• 2003-10-3 2-bromo-1-[3-(trifluoromethyl)phenyl]ethanone 
• 372-31-6 ethyl 4,4,4-trifluoroacetoacetate 
• 349-76-8 3'-(trifluoromethyl)acetophenone 

Downstream Products

• 1027313-56-9 2-[4-(3-Diethylamino-propylcarbamoyl)-5-trifluoromethyl-pyrazol-1-yl]-4-(3-trifluoromethyl-phenyl)-thiazole-5-carboxylic acid methyl ester 
• 159886-03-0 5-Bromo-2-[4-[3-(N,N-diethylamino)propylcarbamoyl]-5-(trifluoromethyl)pyrazol-1-yl]-4-(3-trifluoromethylphenyl)-thiazole 
• 1025873-47-5 5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-thiazol-2-yl]-1H-pyrazole-4-carboxylic acid (3-azido-propyl)-amide 
• 1026655-81-1 5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-thiazol-2-yl]-1H-pyrazole-4-carboxylic acid (3-cyano-propyl)-amide 
• 1026813-13-7 5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-thiazol-2-yl]-1H-pyrazole-4-carboxylic acid (4-imino-butyl)-amide 
• 159886-35-8 2-[4-(3-Bromopropylcarbamoyl)-5-(trifluoromethyl)pyrazol-1-yl]-4-(3-trifluoromethylphenyl)thiazole 
• 159885-84-4 1-[5-Bromo-4-(3-trifluoromethyl-phenyl)-thiazol-2-yl]-5-trifluoromethyl-1H-pyrazole-4-carboxylic acid 
• 159885-76-4 1-[5-Bromo-4-(3-trifluoromethyl-phenyl)-thiazol-2-yl]-5-trifluoromethyl-1H-pyrazole-4-carboxylic acid ethyl ester 

Relevant articles and documents

Novel thiazole-based heterocycles as selective inhibitors of fibrinogen- mediated platelet aggregation

The synthesis and biological activity of novel thiazole-based heterocycles as inhibitors of thrombin-induced human platelet aggregation are described. Further evaluation of selected compounds show they inhibit platelet aggregation as stimulated by a varie

Substituted thiazole derivatives useful as platelet aggregation inhibitors

This invention relates to substituted thiazole derivatives of the following general formula, the substituent groups of which are as defined herein: STR1 These compounds are useful as inhibitors of platelet aggregation and inhibitors of adhesion molecules and may be provided in pharmaceutical compositions and in methods of treating reperfusion thrombosis injury in patients.